Allergen-specific IgG antibodies in cats with allergic skin disease

被引：12
|
作者：
Foster, AP
O'Dair, HA
DeBoer, DJ
机构：
[1] Univ Bristol, Dept Vet Clin Sci, Div Compan Anim, Langford BS40 5DU, Somerset, England
[2] Univ Wisconsin, Sch Vet Med, Dept Med Sci, Madison, WI 53706 USA
来源：
RESEARCH IN VETERINARY SCIENCE | 1997年 / 63卷 / 03期
关键词：
D O I：
10.1016/S0034-5288(97)90027-8
中图分类号：
S85 [动物医学（兽医学）];
学科分类号：
0906 ;
摘要：
An enzyme-linked immunosorbent assay was developed for quantifying feline serum allergen-specific IgG directed against selected house dust, pollen and flea allergens. The assay was used to compare allergen-specific IgG concentrations in sera from healthy cats, cats with non-dermatologic illness, confirmed allergic cats and undiagnosed pruritic cats. Our results demonstrate that cats with confirmed allergic skin disease have significantly more IgG directed against house dust, flea and ryegrass allergens than other cat groups examined. These results support the theory that cats with allergic skin disease have an underlying T-H2 lymphocyte response that directs production of both allergen specific IgG and IgE.
引用
收藏
页码：239 / 243
页数：5
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