Biofunctional properties of Eruca sativa Miller (rocket salad) hydroalcoholic extract

被引:6
|
作者
Sultan, Khushbakht [1 ]
Zakir, Muhammad [1 ]
Khan, Haroon [2 ]
Rauf, Abdur [3 ]
Ul Akber, Noor [4 ]
Khan, Murad Ali [1 ]
机构
[1] Kohat Univ Sci & Technol, Dept Chem, Kohat, Pakistan
[2] Abdul Wali Khan Univ Mardan, Dept Pharm, Mardan 23200, Pakistan
[3] Univ Peshawar, Inst Chem Sci, Peshawar 25120, Kpk, Pakistan
[4] Kohat Univ Sci & Technol, Dept Zool, Kohat, Pakistan
关键词
Eruca sativa Miller; rocket salad; hypoglycaemic activity; antioxidant;
D O I
10.1080/14786419.2015.1046380
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
Eruca sativa Miller is a worldwide common alimentary plant (rocket leaves). The aim of this study was to correlate the potential in vitro scavenging activity of the E. sativa hydroalcoholic extract (HAE) with its in vivo hypoglycaemic effect. In DDPH free radical (DFR) and ferric-reducing antioxidant power assays, HAE in a concentration dependent manner (25-100g/mL) displayed a strong scavenging activity with maximum effect of 88% and 75% at 100g/mL, respectively. Daily administration of HAE (50mg/kg; p.o.) in the in vivo model of alloxan-induced diabetic rabbits for 28 days showed significant reduction in glycaemia, also supported by recovery of body weight. In conclusion, our results give preliminary information on the potential use of this plant as a nutraceutical, useful to control and/or prevent a hyperglycaemic status.
引用
收藏
页码:1202 / 1204
页数:3
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