Hematopoietic Stem Cell Transplantation after Posttransplant Lymphoproliferative Disorder

被引：2
|
作者：
Kim, Min Joo [1 ]
Kim, Inho [1 ]
Bae, Hyun-Mi [1 ]
Seo, Kyungsuk [2 ]
Park, Namjun [2 ]
Yoon, Sung-Soo [1 ]
Park, Seonyang [1 ]
Kim, Byoung Kook [1 ]
机构：
[1] Seoul Natl Univ, Coll Med, Dept Internal Med, Seoul 110744, South Korea
[2] Seoul Natl Univ, Coll Med, Dept Surg, Seoul 110744, South Korea
来源：
JOURNAL OF KOREAN MEDICAL SCIENCE | 2010年 / 25卷 / 05期
关键词：
Posttransplant Lymphoproliferative Disorder; Hematopoietic Stem Cell Transplantation; Liver Transplantation; EPSTEIN-BARR-VIRUS; BONE-MARROW-TRANSPLANTATION; CYTOTOXIC T-CELLS; ORGAN-TRANSPLANTATION; DISEASE; RISK; RITUXIMAB; RECIPIENTS; INFECTION; ANTIBODY;
D O I：
10.3346/jkms.2010.25.5.781
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
A 16-yr-old girl received liver transplantation for fulminant hepatitis. Aplastic anemia developed, and she received hematopoietic stem cell transplantation (HSCT). Eleven months after liver transplantation, abdominal lymph node enlargement and colon ulcers were observed, and colon biopsy showed posttransplant lymphoproliferative disorder (PTLD). Immunosuppression reduction was attempted, but it produced no therapeutic effect. Fourteen months after liver transplantation, she received a second HSCT due to engraftment failure, and PTLD resolved completely. The second HSCT can serve as cellular therapy for PTLD.
引用
收藏
页码：781 / 784
页数：4
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