Recent developments and future directions in computational genomics

被引：45
|
作者：
Tsoka, S [1 ]
Ouzounis, CA [1 ]
机构：
[1] EMBL, European Bioinformat Inst, Computat Gen Grp, Res Programme,Cambridge Outstn, Cambridge CB10 1SD, England
来源：
FEBS LETTERS | 2000年 / 480卷 / 01期
基金：
英国医学研究理事会;
关键词：
genomics; bioinformatics; algorithm; molecular biology database; genomic context; systems modelling; knowledge representation;
D O I：
10.1016/S0014-5793(00)01776-2
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Computational genomics is a subfield of computational biology that deals with the analysis of entire genome sequences. Transcending the boundaries of classical sequence analysis, computational genomics exploits the inherent properties of entire genomes by modelling them as systems. We review recent developments in the field, discuss in some detail a number of novel approaches that take into account the genomic context and argue that progress will be made by novel knowledge representation and simulation technologies. (C) 2000 Federation of European Biochemical Societies. Published by Elsevier Science B.V. All rights reserved.
引用
收藏
页码：42 / 48
页数：7
相关论文
共 50 条
  • [1] Evaluative conditioning: Recent developments and future directions
    Gast, Anne
    Gawronski, Bertram
    De Houwer, Jan
    [J]. LEARNING AND MOTIVATION, 2012, 43 (03) : 79 - 88
  • [2] Capsule endoscopy - Recent developments and future directions
    Chetcuti Zammit, Stefania
    Sidhu, Reena
    [J]. EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY, 2021, 15 (02) : 127 - 137
  • [3] Identity and Change: Recent Developments and Future Directions
    Price, Deborah
    van Dick, Rolf
    [J]. JOURNAL OF CHANGE MANAGEMENT, 2012, 12 (01) : 7 - 11
  • [4] IMMUNOASSAY - RECENT DEVELOPMENTS AND FUTURE-DIRECTIONS
    EKINS, R
    [J]. NUCLEAR MEDICINE AND BIOLOGY, 1994, 21 (03) : 495 - 521
  • [5] Solidification microstructures: Recent developments, future directions
    Boettinger, WJ
    Coriell, SR
    Greer, AL
    Karma, A
    Kurz, W
    Rappaz, M
    Trivedi, R
    [J]. ACTA MATERIALIA, 2000, 48 (01) : 43 - 70
  • [6] Recent developments and future directions in SERS for bioanalysis
    Harper, Mhairi M.
    McKeating, Kristy S.
    Faulds, Karen
    [J]. PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2013, 15 (15) : 5312 - 5328
  • [7] Recent Developments and Future Directions at Energy Policy
    Brown, Stephen P. A.
    Jefferson, Michael
    Brown, Marilyn A.
    Madlener, Reinhard
    Thomas, Stephen D.
    Thou, Peng
    [J]. ENERGY POLICY, 2018, 121 : A1 - A2
  • [8] Memory rehabilitation - Recent developments and future directions
    Thone, AIT
    [J]. RESTORATIVE NEUROLOGY AND NEUROSCIENCE, 1996, 9 (03) : 125 - 140
  • [9] Neurovisual rehabilitation: recent developments and future directions
    Kerkhoff, G
    [J]. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2000, 68 (06): : 691 - 706
  • [10] The Terebelliformia-Recent Developments and Future Directions
    Hutchings, Pat
    Carrerette, Orlemir
    Nogueira, Joao M. M.
    Hourdez, Stephane
    Lavesque, Nicolas
    [J]. DIVERSITY-BASEL, 2021, 13 (02): : 1 - 32
12345