Genotoxicity study of high aspect ratio silver nanowires

被引:5
|
作者
Charehsaz, Mohammad [1 ]
Coskun, Sahin [2 ]
Unalan, Husnu Emrah [2 ]
Reis, Rengin [1 ]
Helvacioglu, Sinem [1 ]
Giri, Ashok Kumar [3 ]
Aydin, Ahmet [1 ]
机构
[1] Yeditepe Univ, Dept Toxicol, Fac Pharm, Istanbul, Turkey
[2] Middle East Tech Univ, Dept Met & Mat Engn, Ankara, Turkey
[3] CSIR Indian Inst Chem Biol, Div Mol Genet, Kolkata, India
来源
关键词
Silver nanowires; mutagenicity; in vivo chromosomal aberration test; Ames test; IN-VITRO; NANOPARTICLES; CELLS; MITOCHONDRIA; INFLAMMATION; GENERATION; RESPONSES; TOXICITY; LENGTH; VIVO;
D O I
10.1080/02772248.2016.1276581
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
The genotoxicity potential of silver nanowires synthesized via the solution-based polyol method has been investigated. They were found to be non-mutagenic in three Salmonella strains and were not genotoxic in a clastogenicity assay in mice. Residual surfactant was found to have an effect on the toxicological properties of the nanowires by increasing the rate of Ag+ release. Residual surfactant can be easily degraded via a UV treatment.
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页码:837 / 847
页数:11
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