Proteins involved in Campylobacter jejuni 81-176 recovery after high-pressure treatment

被引:3
|
作者
Bieche, Clemence [1 ,2 ]
de Lamballerie, Marie [2 ]
Federighi, Michel [1 ]
Le Bail, Alain [2 ]
Tresse, Odile [1 ]
机构
[1] Ecole Natl Vet Nantes, UMR INRA SECALIM ENVN ENITIAA 1014, F-44307 Nantes 3, France
[2] ENITIAA, GEPEA, CNRS, UMR 6144, Nantes, France
关键词
Campylobacter jejuni; high pressure; recovery; protein synthesis; metabolic pathway; HIGH HYDROSTATIC-PRESSURE; STRESS-RESPONSE; INACTIVATION; RESISTANCE; HEAT;
D O I
10.1111/j.1749-6632.2009.05180.x
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Campylobacteriosis has been recognized as the major bacterial food-borne infection worldwide. Campylobacter, especially C. jejuni, contaminate mainly poultry meat. Although more sensitive than other food-borne pathogens to many stresses, C. jejuni can survive food processing and go on to reach its final reservoir (the human gut). Genomic analyses of this organism indicate a lack of genes described in other gram-negative bacteria to overcome stresses. The high-pressure recovery response of C. jejuni 81-176 was analyzed from two-dimensional electrophoretic profiles of the cytoplasmic proteome. The main cellular mechanisms controlling the down- and upregulated proteins are discussed.
引用
收藏
页码:133 / 138
页数:6
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