Bayesian inference for asymptomatic COVID-19 infection rates

被引:1
|
作者
Cahoy, Dexter [1 ]
Sedransk, Joseph [2 ]
机构
[1] Univ Houston Downtown, Dept Math & Stat, Houston, TX 77002 USA
[2] Univ Maryland, Joint Program Survey Methodol, College Pk, MD 20742 USA
关键词
dirichlet process mixture; exchangeable random variables; meta-analysis; pooling results; reversible jump Markov Chain Monte Carlo; SARS-CoV-2; METAANALYSIS;
D O I
10.1002/sim.9408
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
To strengthen inferences meta-analyses are commonly used to summarize information from a set of independent studies. In some cases, though, the data may not satisfy the assumptions underlying the meta-analysis. Using three Bayesian methods that have a more general structure than the common meta-analytic ones, we can show the extent and nature of the pooling that is justified statistically. In this article, we reanalyze data from several reviews whose objective is to make inference about the COVID-19 asymptomatic infection rate. When it is unlikely that all of the true effect sizes come from a single source researchers should be cautious about pooling the data from all of the studies. Our findings and methodology are applicable to other COVID-19 outcome variables, and more generally.
引用
收藏
页码:3131 / 3148
页数:18
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