Halogenated Indole Alkaloids from Marine Invertebrates

被引：75
|
作者：
Pauletti, Patricia Mendonca [1 ]
Cintra, Lucas Silva [1 ]
Braguine, Caio Guedes [1 ]
da Silva Filho, Ademar Alves [1 ]
Andrade e Silva, Marcio Luis [1 ]
Cunha, Wilson Roberto [1 ]
Januario, Ana Helena [1 ]
机构：
[1] Univ Franca, Nucleo Pesquisas Ciencias Exatas & Tecnol, BR-14404600 Sao Paulo, Brazil
来源：
MARINE DRUGS | 2010年 / 8卷 / 05期
基金：
巴西圣保罗研究基金会;
关键词：
marine invertebrates; halogenated indole alkaloids; structure elucidation; bioactivity; C-13-NMR spectral data; SPONGE KIRKPATRICKIA-VARIALOSA; APLYSINOPSIN-TYPE ALKALOIDS; PROTEIN-KINASE INHIBITORS; VARIOLIN-B; FAMILY DENDROPHYLLIIDAE; ANTARCTIC SPONGE; NATURAL-PRODUCTS; A-C; SCLERACTINIAN CORALS; IMIDAZOLE ALKALOIDS;
D O I：
10.3390/md8051526
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
This review discusses the isolation, structural elucidation, and biological activities of halogenated indole alkaloids obtained from marine invertebrates. Meridianins and related compounds (variolins, psammopemmins, and aplicyanins), as well as aplysinopsins and leptoclinidamines, are focused on. A compilation of the C-13-NMR spectral data of these selected natural indole alkaloids is also provided.
引用
收藏
页码：1526 / 1549
页数：24
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