Tumor Immunology and Immunotherapy for Head and Neck Squamous Cell Carcinoma

被引：17
|
作者：
Moskovitz, J. M. [1 ]
Ferris, R. L. [2 ]
机构：
[1] Univ Pittsburgh, Dept Otolaryngol, 200 Lothrop St,Suite 300, Pittsburgh, PA 15213 USA
[2] UPMC Hillman Canc Ctr, Pittsburgh, PA USA
来源：
JOURNAL OF DENTAL RESEARCH | 2018年 / 97卷 / 06期
关键词：
cancer biology; clinical trials; checkpoint receptors; immune resistance; T lymphocyte; neoadjuvant immunotherapy; IMMUNE-CHECKPOINT BLOCKADE; CHRONIC VIRAL-INFECTION; CANCER-IMMUNOTHERAPY; COMBINED NIVOLUMAB; RESPONSE CRITERIA; ADVANCED MELANOMA; T-CELLS; RESISTANCE; THERAPY; PEMBROLIZUMAB;
D O I：
10.1177/0022034518759464
中图分类号：
R78 [口腔科学];
学科分类号：
1003 ;
摘要：
The immune system plays an important role in the evolution of malignancy and has become an important target for novel antineoplastic agents. This review article focuses on key features of tumor immunology, including the role of immunotherapy in general and as it pertains to head and neck squamous cell carcinoma. Side effects, resistance mechanisms, and therapeutic monitoring strategies pertaining to immunotherapy are discussed.
引用
收藏
页码：622 / 626
页数：5
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