PHENOLIC CONTENT, ANTIOXIDANT ACTIVITY AND PHARMACEUTICAL AVAILABILITY OF HYDROGELS WITH EXTRACTS OF ROSMARINUS OFFICINALIS L. AND SAMBUCUS NIGRA L.

被引:6
|
作者
Michalak, Monika [1 ]
Zielinska, Agnieszka [2 ]
Paradowska, Katarzyna [2 ]
机构
[1] Jan Kochanowski Univ, Coll Med, Inst Med Sci, Dept Dermatol Cosmetol & Aesthet Surg, IX Wiekow Kielce 19a, PL-25317 Kielce, Poland
[2] Med Univ Warsaw, Fac Pharm, Dept Phys Chem, Chair Phys Pharm & Bioanal, Banacha 1, PL-02097 Warsaw, Poland
来源
ACTA POLONIAE PHARMACEUTICA | 2021年 / 78卷 / 02期
关键词
antioxidant; pharmaceutical availability; plant extract; polyphenols; Rosmarinus officinalis; Sambucus nigra; VITRO SKIN PERMEATION; OXIDATIVE STRESS; POLYPHENOLS; RELEASE; EPIDERMIS; ACID;
D O I
10.32383/appdr/134000
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
New active ingredients, including those of plant origin, are still sought in the pharmaceutical and cosmetics industry. The present study was focused on the determination of the polyphenolic content and the confirmation of antioxidant properties of rosemary and elderflower extracts. Investigations were also carried out to define the pharmaceutical availability of hydrogels with the tested extracts. This study has demonstrated that the extract of rosemary herb is characterized by greater DPPH scavenging activity. It also contains a higher content of polyphenols, including flavonoids. The research of diffusion capacity of plant extracts from hydrogels showed that the extract from rosemary herb is more efficiently released. Extracts of Rosmarinus officinalis L. and Sambucus nigra L. can be used as natural products with high antioxidant properties.
引用
收藏
页码:219 / 226
页数:8
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