Based on the theoretical framework of the materialist Discourse Analysis, this paper aims to analyze the discourse on vaccination against the new coronavirus. In order to do so, it takes contemporary digital textualities that circulate on Twitter as its main corpus, by observing for this the way the linguistic marks-present in the selected textualities-work. A(n informational) war on the vaccine is being produced: favorable and contrary meanings circulate. They echo effects of meanings that have crossed other historical moments through a work of discursive memory. As a result of this movement of meanings, we constituted a secondary corpus with cartoons published in newspapers of the early 20th century and images posted on another social network, Facebook. By working in the midst of different textualities, we promote a gesture of interpretation that intends the constitution of the anti-science discourse, in the interrelation with the conservative discourse.