Lack of a role for CYP1A2 in the activation of 4-aminobiphenyl into DNA-reactive metabolites in mice.

被引：0
|
作者：
Clay, CD
Tsuneoka, Y
Dalton, TP
Shertzer, HG
Miller, ML
Nebert, DW
机构：
[1] Univ Cincinnati, Med Ctr, Ctr Environm Genet, Cincinnati, OH 45267 USA
[2] Univ Cincinnati, Med Ctr, Dept Environm Hlth, Cincinnati, OH 45267 USA
来源：
TOXICOLOGICAL SCIENCES | 2003年 / 72卷
关键词：
D O I：
暂无
中图分类号：
R99 [毒物学（毒理学）];
学科分类号：
100405 ;
摘要：
1632
引用
收藏
页码：336 / 336
页数：1
相关论文
共 50 条
  • [1] Relative Contributions of CYP1A2 and CYP2E1 to the Bioactivation and Clearance of 4-Aminobiphenyl in Adult Mice
    Wang, Shuang
    Bott, Debbie
    Tung, Aveline
    Sugamori, Kim S.
    Grant, Denis M.
    DRUG METABOLISM AND DISPOSITION, 2015, 43 (07) : 916 - 921
  • [2] 4-aminobiphenyl-induced liver and urinary bladder DNA adduct formation in Cyp1a2(-/-) and Cyp1a2(+/+) mice
    Tsuneoka, Y
    Dalton, TP
    Miller, ML
    Clay, CD
    Shertzer, HG
    Talaska, G
    Medvedovic, M
    Nebert, DW
    JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2003, 95 (16) : 1227 - 1237
  • [3] CYP1A2 and uroporphyria development in mice.
    Gunsolly, CA
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2002, 223 : U226 - U227
  • [4] CYP1A2 and uroporphyria development in mice.
    Gunsolly, CA
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2002, 223 : U150 - U150
  • [5] CYP1A2 and NAT2 phenotyping and 3-aminobiphenyl and 4-aminobiphenyl hemoglobin adduct levels in smokers and non-smokers
    Sarkar, M
    Stabbert, R
    Kinser, RD
    Oey, J
    Rustemeier, K
    von Holt, K
    Schepers, G
    Walk, RA
    Roethig, HJ
    TOXICOLOGY AND APPLIED PHARMACOLOGY, 2006, 213 (03) : 198 - 206
  • [6] CYP1A2 is not the primary enzyme responsible for 4-aminobiphenyl-induced hepatocarcinogenesis in mice
    Kimura, S
    Kawabe, M
    Ward, JM
    Morishima, H
    Kadlubar, FF
    Hammons, GJ
    Fernandez-Salguero, P
    Gonzalez, FJ
    CARCINOGENESIS, 1999, 20 (09) : 1825 - 1830
  • [7] Decrease in 4-aminobiphenyl-induced methemoglobinemia in Cyp1a2(-I-) knockout mice
    Shertzer, HG
    Dalton, TP
    Talaska, G
    Nebert, DW
    TOXICOLOGY AND APPLIED PHARMACOLOGY, 2002, 181 (01) : 32 - 37
  • [8] Role of CYP1A2 in the hepatotoxicity of acetaminophen:: Investigations using Cyp1a2 null mice
    Tonge, RP
    Kelly, EJ
    Bruschi, SA
    Kalhorn, T
    Eaton, DL
    Nebert, DW
    Nelson, SD
    TOXICOLOGY AND APPLIED PHARMACOLOGY, 1998, 153 (01) : 102 - 108
  • [9] Role of CYP1A2 in caffeine pharmacokinetics and metabolism: Studies using mice deficient in CYP1A2
    Buters, JTM
    Tang, BK
    Pineau, T
    Gelboin, HV
    Kimura, S
    Gonzalez, FJ
    PHARMACOGENETICS, 1996, 6 (04): : 291 - 296
  • [10] Potential Role of Cytochrome P450-1B1 in the Metabolic Activation of 4-Aminobiphenyl in Humans
    Ketelslegers, Hans B.
    Godschalk, Roger W. L.
    Eskens, Bart J. M.
    Dallinga, Jan W.
    Gottschalk, Ralph W. H.
    van Schooten, Frederik J.
    van Delft, Joost H. M.
    Kleinjans, Jos C. S.
    MOLECULAR CARCINOGENESIS, 2009, 48 (08) : 685 - 691
12345