Long-term side effects of glucocorticoids

被引：544
|
作者：
Oray, Merih [1 ,2 ,3 ]
Abu Samra, Khawla [1 ,2 ]
Ebrahimiadib, Nazanin [1 ,2 ]
Meese, Halea [1 ,2 ]
Foster, C. Stephen [1 ,2 ,4 ]
机构：
[1] Massachusetts Eye Res & Surg Inst, 1440 Main St, Waltham, MA 02142 USA
[2] Ocular Immunol & Uveitis Fdn, Waltham, MA USA
[3] Istanbul Univ, Istanbul Fac Med, Dept Ophthalmol, Istanbul, Turkey
[4] Harvard Univ, Sch Med, Dept Ophthalmol, Boston, MA USA
来源：
EXPERT OPINION ON DRUG SAFETY | 2016年 / 15卷 / 04期
关键词：
glucocorticoids; immunosuppression; side effects; corticosteroids; RHEUMATOID-ARTHRITIS; INDUCED OSTEOPOROSIS; ADVERSE EVENTS; RECEPTOR AGONISTS; PEPTIC-ULCER; RISK-FACTORS; CORTICOSTEROIDS; THERAPY; COMPLICATIONS; DISEASE;
D O I：
10.1517/14740338.2016.1140743
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Introduction: Glucocorticoids represent the standard therapy for reducing inflammation and immune activation in various diseases. However, as with any potent medication, they are not without side effects. Glucocorticoid-associated side effects may involve most major organ systems. Musculoskeletal, gastrointestinal, cardiovascular, endocrine, neuropsychiatric, dermatologic, ocular, and immunologic side effects are all possible.Areas Covered: This article analyzes English-language literature and provides an update on the most recent literature regarding side effects of systemic glucocorticoid treatment.Expert Opinion: The risk/benefit ratio of glucocorticoid therapy can be improved by proper use. Careful monitoring and using appropriate preventive strategies can potentially minimize side effects.
引用
收藏
页码：457 / 465
页数：9
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