Clinical Effect of Electroacupuncture on Lung Injury Patients Caused by Severe Acute Pancreatitis

This study aimed to investigate the effects of electroacupuncture at the Lieque, Chize, and Zusanli points in patients with lung injury caused by severe acute pancreatitis. Patients with acute respiratory distress syndrome (ARDS) induced by severe acute pancreatitis (SAP) were randomly divided into three groups based on the treatment: conventional therapy alone (group A), electroacupuncture of nonacupoints with conventional therapy (group B), and electroacupuncture at the Lieque (LU7), Chize (LU5), and Zusanli (ST36) points (group C) once a day for 5 days. Arterial blood samples were obtained for blood gas analysis before electroacupuncture (T1) and 3 (T2) and 5 (T3) days after electroacupuncture. Theoxygenation index was significantly higher in all groups at T2 and T3 than that at T1, while the APACHE-II scores were decreased significantly. The expression of TNF-alpha was significantly decreased and the IL-10 was significantly increased in all groups at T3. The oxygenation index at T2 and T3 was significantly higher in group C than that in group B. Electroacupuncture at Lieque, Chize, and Zusanli can lessen the lung injury induced by SAP, and the mechanism may be related to the decreased TNF-alpha and increased IL-10 value. Clinical Registration Number is ChiCTR-ICR-15006850.