The Apert S252W mutation in fibroblast growth factor receptor-2 increases apoptosis through PKC, IL-1 and downstream activation of caspases-8 and-3 in human calvaria osteoblasts.

被引：0

|

作者：

Lemonnier, J ^{[1
]}

Haÿ, E ^{[1
]}

Delannoy, P ^{[1
]}

Lomri, A ^{[1
]}

Fromigué, O ^{[1
]}

Marie, PJ ^{[1
]}

机构：

[1] INSERM, U349, Paris, France

来源：

JOURNAL OF BONE AND MINERAL RESEARCH | 2000年 / 15卷

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D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

F134

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页码：S212 / S212

页数：1

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[1] Role of N-cadherin and protein kinase C in osteoblast gene activation induced by the S252W fibroblast growth factor receptor 2 mutation in apert craniosynostosis
Lemonnier, J
Hay, E
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Lomri, A
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JOURNAL OF BONE AND MINERAL RESEARCH, 2001, 16 (05) : 832 - 845
[2] A soluble form of fibroblast growth factor receptor 2 (FGFR2) with S252W mutation acts as an efficient inhibitor for the enhanced osteoblastic differentiation caused by FGFR2 activation in Apert syndrome
Tanimoto, Y
Yokozeki, M
Hiura, K
Matsumoto, K
Nakanishi, H
Matsumoto, T
Marie, PJ
Moriyama, K
JOURNAL OF BIOLOGICAL CHEMISTRY, 2004, 279 (44) : 45926 - 45934