The Role of 18F-FDG PET/CT in Suspected Intraocular Sarcoidosis and Tuberculosis

被引：13
|
作者：
Burger, C. [1 ,2 ]
Holness, J. L. [1 ,2 ]
Smit, D. P. [2 ,3 ]
Griffith-Richards, S. [2 ,4 ]
Koegelenberg, C. F. N. [2 ,5 ]
Ellmann, A. [1 ,2 ]
机构：
[1] Tygerberg Hosp, Div Nucl Med, Francie van Zijl Dr, ZA-7505 Cape Town, South Africa
[2] Stellenbosch Univ, Francie van Zijl Dr, ZA-7505 Cape Town, South Africa
[3] Tygerberg Hosp, Ophthalmol, Cape Town, South Africa
[4] Tygerberg Hosp, Radiodiag, Cape Town, South Africa
[5] Tygerberg Hosp, Pulmonol, Cape Town, South Africa
来源：
OCULAR IMMUNOLOGY AND INFLAMMATION | 2021年 / 29卷 / 03期
关键词：
Uveitis; tuberculosis; sarcoidosis; PET; CT; imaging; POSITRON-EMISSION-TOMOGRAPHY; COMPUTERIZED-TOMOGRAPHY; OCULAR TUBERCULOSIS; UVEITIS; CHEST; DIAGNOSIS; PATTERNS;
D O I：
10.1080/09273948.2019.1685109
中图分类号：
R77 [眼科学];
学科分类号：
100212 ;
摘要：
Purpose: To determine the utility of fluorine-18 fluorodeoxyglucose Positron Emission Tomography Computed Tomography (FDG PET/CT) in patients with suspected ocular sarcoidosis (OS) or intraocular tuberculosis (IOTB) in a resource-constrained, TB endemic area. Methods: Independent review of the FDG PET/CTs, Computed Tomography (CT) scans and chest radiographs (CXRs) of patients with suspected OS or IOTB and inconclusive conventional workup. Results: Twenty-nine PET/CTs and CXRs were reviewed, with 38% of PET/CTs and CTs demonstrating evidence of TB or sarcoidosis, compared to 21% of CXRs. The sensitivity, specificity, positive and negative predictive values for PET/CT and CT were similar - 85.7%, 95.5%, 85.7% and 95.5% for OS, and 33.3%, 100%, 100% and 68% for IOTB respectively and for CXR, 57.1%, 100%, 100% and 88% for OS, and 16.7%, 100%, 100% and 63% for IOTB. Conclusion: PET/CT added no significant additional benefit over Chest CT in patients with suspected OS or IOTB.
引用
收藏
页码：530 / 536
页数：7
相关论文
共 50 条
  • [1] Diagnostic Role of 18F-FDG PET/CT in the Evaluation of Patients with Suspected Intraocular Lesions
    Kumar, G.
    Karunanithi, S.
    Roy, S. Guha
    Kumar, R.
    [J]. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2014, 41 : S457 - S457
  • [2] Role of 18F-FDG PET/CT in the diagnostic challenge of sarcoidosis
    Pabon, L.
    Alvarez, A. M.
    Renjifo, M.
    [J]. REVISTA ESPANOLA DE MEDICINA NUCLEAR E IMAGEN MOLECULAR, 2019, 38 (05): : 322 - 324
  • [3] Role of 18F-FDG PET/CT imaging in Mycobacterium Tuberculosis
    Kasat, A.
    Paunikar, S.
    Gawde, S.
    [J]. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2018, 45 : S324 - S325
  • [4] Assessment of the role of 18F-FDG PET/CT in the diagnosis of cardiac sarcoidosis
    Godoy Bravo, M.
    Frutos Esteban, L.
    Gimeno Blanes, J.
    Ibanez Ibanez, M.
    Reyes Marles, R.
    Sime Loayza, I.
    Mohamed Salem, L.
    Navarro Fernandez, J.
    Castellon Sanchez, M.
    Nicolas Ruiz, F.
    Claver Valderas, M.
    [J]. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2016, 43 : S483 - S483
  • [5] BONE SARCOIDOSIS: USEFULNESS OF 18F-FDG PET/CT
    Demaria, Lucie
    Borie, Raphael
    Benali, Khadija
    Forien, Marine
    Dieude, Philippe
    Crestani, Bruno
    Ottaviani, Sebastien
    [J]. ANNALS OF THE RHEUMATIC DISEASES, 2019, 78 : 2031 - 2031
  • [6] 18F-FDG PET/CT for the Assessment of Myocardial Sarcoidosis
    Skali, Hicham
    Schulman, Allison R.
    Dorbala, Sharmila
    [J]. CURRENT CARDIOLOGY REPORTS, 2013, 15 (04)
  • [7] Muscular sarcoidosis in the eyes of 18F-FDG PET/CT
    Milojevic, Isidora Grozdic
    Sobic-Saranovic, Dragana
    Milojevic, Bogomir
    Artiko, Vera M.
    [J]. JOURNAL OF CLINICAL ULTRASOUND, 2022, 50 (03) : 399 - 404
  • [8] The utility of 18F-FDG PET/CT in chronic sarcoidosis
    Videnovic-Ivanov, Jelica
    Sobic-Saranovic, Dragana
    Vucinic, Violeta
    Grozdic, Isidora
    Filipovic, Snezana
    Stjepanovic, Mihailo
    Omcikus, Maja
    [J]. EUROPEAN RESPIRATORY JOURNAL, 2013, 42
  • [9] 18F-FDG PET/CT for the Assessment of Myocardial Sarcoidosis
    Hicham Skali
    Allison R. Schulman
    Sharmila Dorbala
    [J]. Current Cardiology Reports, 2013, 15
  • [10] 18F-FDG PET-CT - an evolving role in management of tuberculosis
    Singla, S.
    Kumar, R.
    Bal, C. S.
    Dhull, V. S.
    Sharma, P.
    Jain, T.
    Sahoo, M.
    Malhotra, A.
    [J]. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2012, 39 : S604 - S604
12345