14th International HLA and Immunogenetics Workshop: Report on the structural basis of HLA compatibility

被引：12
|
作者：
Duquesnoy, R. J.
Claas, F. H. J.
机构：
[1] Univ Pittsburgh, Ctr Med, Thomas E Starzl Transplantat Inst, Div Transplantat Pathol, Pittsburgh, PA 15261 USA
[2] Leiden Univ, Dept Immunohematol & Blood Transfus, Ctr Med, NL-2300 RA Leiden, Netherlands
来源：
TISSUE ANTIGENS | 2007年 / 69卷
关键词：
eplet; HLAMatchmaker; HLA; histocompatibility;
D O I：
10.1111/j.1399-0039.2006.00766.x
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Under auspices of the 14th International Human Leukocyte Antigen (HLA) and Immunogenetics Workshop, multilaboratory collaborative studies were organized addressing the following projects: (1) identification of structurally defined class I and class II HLA epitopes by human monoclonal antibodies, (2) assessment of the relative immunogenicity of structurally defined donor HLA mismatches in kidney transplantation, and (3) evaluation of the usefulness of structurally based HLA matching in platelet transfusion support of alloimmunized thrombocytopenic patients. This progress report describes a preliminary HLAMatchmaker-based data analysis in each project. The findings support the clinical usefulness of structural HLA matching.
引用
收藏
页码：180 / 184
页数：5
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