Matrix-assisted laser desorption/ionization mass spectrometry of carbohydrates and glycoconjugates

被引:140
|
作者
Harvey, DJ [1 ]
机构
[1] Oxford Glycobiol Inst, Dept Biochem, Oxford OX1 3QU, England
关键词
carbohydrates; matrix-assisted laser desorption/ionization (MALDI); matrix; fragmentation; glycoproteins;
D O I
10.1016/S1387-3806(02)00968-5
中图分类号
O64 [物理化学(理论化学)、化学物理学]; O56 [分子物理学、原子物理学];
学科分类号
070203 ; 070304 ; 081704 ; 1406 ;
摘要
The application of matrix-assisted laser desorption/ionization (MALDI) mass spectrometry to the analysis of carbohydrates and their conjugates with proteins and lipids is reviewed. Among the topics discussed are instrumentation, MALDI matrices, derivatization, fragmentation and application of MALDI to various structural types. (C) 2002 Elsevier Science B.V. All rights reserved.
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页码:1 / 35
页数:35
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