Breast cancer risk in MEN1-a cancer genetics perspective

被引：12
|
作者：
Brennan, Paul [1 ]
机构：
[1] Northern Genet Serv, Newcastle Upon Tyne, Tyne & Wear, England
来源：
CLINICAL ENDOCRINOLOGY | 2015年 / 82卷 / 03期
关键词：
ENDOCRINE NEOPLASIA TYPE-1; OF-THE-LITERATURE; HYPERPARATHYROIDISM; MUTATIONS;
D O I：
10.1111/cen.12614
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The tumour spectrum associated with multiple endocrine neoplasia type 1 (MEN1) has been known for many years. New data suggest that females with MEN1 may face an additional, hitherto unrecognized, risk of early-onset breast cancer. The menin protein is certainly known to have a role in regulating oestrogen receptor activity; but how robust are the data linking MEN1 to breast cancer? This article examines the published data from the viewpoint of a cancer geneticist and considers whether there really is a justifiable indication for enhanced breast surveillance in women with MEN1.
引用
收藏
页码：327 / 329
页数：3
相关论文
共 50 条
  • [1] Reply to: Breast cancer risk in MEN1-a cancer genetics perspective
    Dreijerink, Koen M. A.
    Valk, Gerlof D.
    [J]. CLINICAL ENDOCRINOLOGY, 2015, 83 (01) : 141 - 141
  • [2] Men diagnosed with breast cancer: Reflections on genetics
    Iredale, Rachel
    Hafner, J.
    Sivell, S.
    Brain, K.
    France, L.
    Williams, B.
    Gray, J.
    [J]. JOURNAL OF MEDICAL GENETICS, 2006, 43 : S106 - S106
  • [3] Breast Cancer: Genetics and Risk Assessment
    Tejada-Berges, Trevor
    [J]. CLINICAL OBSTETRICS AND GYNECOLOGY, 2016, 59 (04): : 673 - 687
  • [4] Risk of second primary cancer in men with breast cancer
    Sacha Satram-Hoang
    Argyrios Ziogas
    Hoda Anton-Culver
    [J]. Breast Cancer Research, 9
  • [5] Risk of second primary cancer in men with breast cancer
    Satram-Hoang, Sacha
    Ziogas, Argyrios
    Anton-Culver, Hoda
    [J]. BREAST CANCER RESEARCH, 2007, 9 (01)
  • [6] Risk of subsequent cancer following breast cancer in men
    Auvinen, A
    Curtis, RE
    Ron, E
    [J]. JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2002, 94 (17) : 1330 - 1332
  • [7] The genetics of breast cancer: risk factors for disease
    Collins, Andrew
    Politopoulos, Ioannis
    [J]. APPLICATION OF CLINICAL GENETICS, 2011, 4 : 11 - 19
  • [8] Identification of personal risk of breast cancer: genetics
    Eccles, Diana M.
    [J]. BREAST CANCER RESEARCH, 2008, 10 (Suppl 4)
  • [9] Identification of personal risk of breast cancer: genetics
    Diana M Eccles
    [J]. Breast Cancer Research, 10
  • [10] Putting the risk of breast cancer in perspective
    Phillips, KA
    Glendon, G
    Knight, JA
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 1999, 340 (02): : 141 - 144
12345