Antimicrobial Metabolites from Endophytic Streptomyces sp YIM61470

被引:0
|
作者
Yang, Xueqiong [1 ]
Liu, Yun [1 ]
Li, Shuquan [1 ]
Yang, Fangfang [1 ]
Zhao, Lixing [2 ]
Peng, Li [1 ]
Ding, Zhongtao [1 ]
机构
[1] Yunnan Univ, Sch Chem Sci & Technol, Key Lab Med Chem Nat Resource, Minist Educ, Kunming 650091, Peoples R China
[2] Yunnan Univ, Yunnan Inst Microbiol, Kunming 650091, Peoples R China
基金
中国国家自然科学基金;
关键词
Streptomyces sp; Chiral monoacylglycerol; Spectral analysis; GLYCEROL;
D O I
暂无
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Six compounds were isolated from Streptomyces sp. YIM61470, and their structures elucidated by spectral analysis as (R)-l-O-(phenylacetyl)glycerol (1), 4',5-dihydroxy-6-(3,3-dimethylallyl)-7-methoxyflavanone (2), (32R,33R,34S) -32,33,34,35-bacteriohopanetetrol (3), MKN-003C (4), cyclo (L-Pro-L-Gly) (5), and cyclo(L-Pro-L-Tyr) (6). Compound 1, an chiral monoacylglycerol, was isolated from a natural source for the first time. Compound 2 was first found in microorganisms, and compound 3, a bacteriohopanoid, was found first in the genus Streptomyces. Compounds 1-6 showed weak anti-microbial activity.
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页码:1287 / 1288
页数:2
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