Antibacterial activity of rhodium, iridium, and ruthenium tripodal phosphine complexes

被引:0
|
作者
Sülü, M
Küçükbay, H [1 ]
Durmaz, R
Günal, S
机构
[1] Inonu Univ, Fac Arts & Sci, Dept Chem, TR-44069 Malatya, Turkey
[2] Inonu Univ, Fac Med, Dept Clin Microbiol, TR-44069 Malatya, Turkey
来源
ARZNEIMITTEL-FORSCHUNG-DRUG RESEARCH | 1998年 / 48卷 / 03期
关键词
iridium complexes; antibacterial activity; in vitro studies; rhodium complexes; ruthenium complexes;
D O I
暂无
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Twenty-eight rhodium, iridium, or ruthenium complexes were evaluated for their in vitro antibacterial activity against Enterococcus faecalis ATCC 29212, Staphylococcus aureus ATCC 29213, Escherichia coli ATCC 25922 and Pseudomonaa aeruginosa ATCC 27853. Ten compounds showed an antibacterial activity against Enterococcus faecalis ATCC 29212 and Staphylococcus aureus ATCC 29213 with a range of the minimum inhibitory concentrations (MICs) between 16 and 125 mu g/ml. None of the compounds exhibited antimicrobial activity against the gram-negative strains E. coli ATCC 25922 or Pseudomonas aeruginosa ATCC 29213 with a concentration range between 4 and 500 mu g/ml.
引用
收藏
页码:291 / 293
页数:3
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