Amino acid deprivation promotes intestinal homeostasis through autophagy

被引:1
|
作者
Galluzzi, Lorenzo [1 ,2 ,3 ,4 ,5 ]
Kroemer, Guido [1 ,2 ,3 ,4 ,6 ,7 ,8 ]
机构
[1] Ctr Rech Cordeliers, Equipe Labellisee Ligue Canc 11, Paris, France
[2] INSERM, U1138, Paris, France
[3] Univ Paris 05, Sorbonne Paris Cite, Paris, France
[4] Univ Paris 06, Paris, France
[5] Gustave Roussy Comprehens Canc Inst, Villejuif, France
[6] Gustave Roussy Comprehens Canc Inst, Metabol & Cell Biol Platforms, Villejuif, France
[7] Hop Europeen Georges Pompidou, AP HP, Pole Biol, Paris, France
[8] Karolinska Univ Hosp, Dept Womens & Childrens Hlth, Stockholm, Sweden
关键词
eIF2a; GCN2; inflammasome; mitophagy; reactive oxygen species;
D O I
10.18632/oncotarget.8841
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:29877 / 29878
页数:2
相关论文
共 50 条
  • [1] Unfolded Proteins Regulates Autophagy and Amino Acid Homeostasis through the Dynamics of CTPS Filaments
    Wang, C.
    Lin, W.
    Pai, L.
    MOLECULAR BIOLOGY OF THE CELL, 2024, 35 (01) : 320 - 321
  • [2] Autophagy and Intestinal Homeostasis
    Patel, Khushbu K.
    Stappenbeck, Thaddeus S.
    ANNUAL REVIEW OF PHYSIOLOGY, VOL 75, 2013, 75 : 241 - 262
  • [3] Amino acid metabolism and autophagy in skeletal development and homeostasis
    Suzuki, Akiko
    Iwata, Junichi
    BONE, 2021, 146
  • [4] Amino acid deprivation disrupts barrier function and induces protective autophagy in intestinal porcine epithelial cells
    Yang, Ying
    Li, Wei
    Sun, Yuli
    Han, Feng
    Hu, Chien-An A.
    Wu, Zhenlong
    AMINO ACIDS, 2015, 47 (10) : 2177 - 2184
  • [5] Amino acid deprivation disrupts barrier function and induces protective autophagy in intestinal porcine epithelial cells
    Ying Yang
    Wei Li
    Yuli Sun
    Feng Han
    Chien-An A. Hu
    Zhenlong Wu
    Amino Acids, 2015, 47 : 2177 - 2184
  • [6] Autophagy as a Gatekeeper of Intestinal Homeostasis
    Li, Xiaoxue
    Lemaitre, Bruno
    DEVELOPMENTAL CELL, 2021, 56 (01) : 5 - 6
  • [7] Iron Deprivation Inhibits mTOR Activity by Regulating Amino Acid Homeostasis
    Shapiro, Jason S.
    Chang, Hsiang-Chun
    Sato, Tatsuya
    Sawicki, Konrad T.
    Shang, Meng
    Bayeva, Marina
    Lopaschuk, Gary
    Blackshear, Perry J.
    Ardehali, Hossein
    CIRCULATION, 2017, 136
  • [8] Intestinal microbial amino acid synthesis and its importance for the amino acid homeostasis of the monogastric host
    Metges, CC
    Loh, G
    PROGRESS IN RESEARCH ON ENERGY AND PROTEIN METABOLISM, 2003, (109): : 579 - 592
  • [9] Autophagy and amino acid homeostasis are required for chronological longevity in Saccharomyces cerevisiae
    Alvers, Ashley L.
    Fishwick, Laura K.
    Wood, Michael S.
    Hu, Doreen
    Chung, Hye S.
    Dunn, William A., Jr.
    Aris, John P.
    AGING CELL, 2009, 8 (04): : 353 - 369
  • [10] Amino acid deprivation in cancer cells with compensatory autophagy induction increases sensitivity to autophagy inhibitors
    Fukui, Takahito
    Yabumoto, Manami
    Nishida, Misuzu
    Hirokawa, Shiori
    Sato, Riho
    Kurisu, Taichi
    Nakai, Miyu
    Hassan, Md. Abul
    Kishimoto, Koji
    MOLECULAR & CELLULAR ONCOLOGY, 2024, 11 (01)