Resting heart rate is associated with metabolic syndrome and predicted 10-year risk of cardiovascular disease: a cross-sectional study???????????10?????????????:???????

BackgroundThis study examined whether resting heart rate (RHR) was associated with metabolic syndrome (MetS) and the 10-year predicted risk of cardiovascular disease in a Chinese population. MethodsThe associations of RHR with MetS and 10-year risk of atherosclerotic cardiovascular diseases (ASCVD) was examined in a cross-sectional study conducted in Shanghai, China (n=9486). ResultsCompared with individuals in the lowest RHR quintile (<= 71b.p.m.), those in the highest quintile (>= 91b.p.m.) had a higher prevalence of MetS (21.2% vs 32.6%, respectively; P<0.001). Logistic regression analyses showed that the multivariate-adjusted odds ratio (OR) and 95% confidence interval (CI) for MetS was 1.13 (1.08-1.18) for each 10-b.p.m. increment of RHR (P<0.0001). Furthermore, RHR was strongly associated with the prevalence of hypertension, high blood glucose, and dyslipidemia, but not with central obesity. A stronger association of RHR with MetS was observed among individuals aged <65years, male, with a body mass index <24kg/m(2), without diabetes, hypertension, abnormal lipids, and insulin resistance than among their counterparts (P<0.05 for all). A significantly higher 10-year risk for ASCVD was observed with each 10-b.p.m. increment in RHR in both men and women (ORs [95% CIs] 1.20 [1.07-1.33] and 1.28 [1.17-1.39], respectively; P-trend=0.002 and<0.0001, respectively). ConclusionsIn this study, RHR was associated with a higher prevalence of MetS and elevated 10-year predicted risk of ASCVD in both Chinese men and women. Whether RHR may serve as an indicator for MetS among relatively healthy individuals requires further investigation. ?? ?????????????????????????10??????????????????? ????????????????(n=9486)???????????????10?????????????(atherosclerotic cardiovascular diseases,ASCVD)??????????? ?????????????(<= 71 b.p.m.)??,??????????(>= 91 b.p.m.)??????????????(???21.2%?32.6%;P<0.001)???Logistic????????,?????????10 b.p.m.,???????(odds ratio,OR)?95%????(confidence interval,CI)?1.13(1.08-1.18,P<0.0001)???,?????????????????????????,?????????????????<65?????BMI <24 kg/m(2)??????????,????????????????,??????????????????????(????P<0.05)??????????10 b.p.m.,??????10?ASCVD???????,?OR(95% CI)???1.20(1.07-1.33)?1.28(1.17-1.39)(P-trend???0.002?<0.0001)? ?????????????,???????????????????10?ASCVD???????????????????????????????????????????????????