Daily photoprotection to prevent photoaging

被引:46
|
作者
Krutmann, Jean [1 ,2 ]
Schalka, Sergio [3 ,4 ]
Watson, Rachel Elizabeth Beatrice [5 ,6 ,7 ,8 ]
Wei, Liu [9 ]
Morita, Akimichi [10 ]
机构
[1] IUF Leibniz Res Inst Environm Med, Dusseldorf, Germany
[2] Heinrich Heine Univ, Fac Med, Dusseldorf, Germany
[3] Univ Sao Paulo, Inst Chem, Med Skin Res Ctr, Sao Paulo, Brazil
[4] Univ Sao Paulo, Inst Chem, Dept Biochem, Sao Paulo, Brazil
[5] Univ Manchester, Ctr Dermatol Res, Salford, Lancs, England
[6] Salford Royal NHS Fdn Trust, Salford, Lancs, England
[7] Univ Manchester, Manchester Inst Collaborat Res Ageing, Manchester, Lancs, England
[8] Manchester Univ NHS Fdn Trust, Manchester Acad Hlth Sci Ctr, NIHR Manchester Biomed Res Ctr, Manchester, Lancs, England
[9] Air Force PLA, Dept Dermatol, Gen Hosp, Beijing, Peoples R China
[10] Nagoya City Univ, Dept Geriatr & Environm Dermatol, Grad Sch Med Sci, Nagoya, Aichi, Japan
关键词
photoaging; photoprotection; pigmentary disorders; sunscreens; wrinkles; VISIBLE-LIGHT; HUMAN SKIN; SUNSCREEN USE; DOUBLE-BLIND; INFRARED RADIATION; CLINICAL SIGNS; CHINESE; SUN; EXPRESSION; POLLUTION;
D O I
10.1111/phpp.12688
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Background Extrinsic skin aging or photoaging was previously thought to be almost exclusively due to solar ultraviolet (UV) radiation. However, recent literature has described other contributing factors and clarification is thus required as to what extent and what type of daily photoprotection is needed to mitigate extrinsic skin aging. Methods We reviewed the existing scientific evidence on daily photoprotection, and specific requirements at the product level, to prevent extrinsic skin aging. We critically reviewed the existing evidence on potential ecological and toxicological risks which might be associated with daily photoprotection. Results Evidence shows that broad protection against the entire solar range of UVB, UVA, UVA1, visible light, and short infrared (IRA) is required to prevent extrinsic aging. Other exposome factors, such as air pollution and smoking, also contribute to skin aging. Daily broad-spectrum sunscreen photoprotection should thus contain antioxidant ingredients for additional benefits against UV, IRA, and pollution-induced oxidative stress as well as anti-aging active ingredients to provide clinical benefits against skin aging signs, such as wrinkles and dark spots. Broad-spectrum sunscreen containing pigments, such as iron oxide, may be required for melasma prevention. There is no conclusive clinical evidence that daily sunscreen use is unsafe or that it compromises vitamin D synthesis. Conclusion Daily use of broad-spectrum sunscreen containing antioxidant and anti-aging active ingredients can effectively reduce extrinsic aging.
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页码:482 / 489
页数:8
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