The role of birds in dissemination of Francisella tularensis: first direct molecular evidence for bird-to-human transmission

被引:23
|
作者
Padeshki, P. I. [1 ]
Ivanov, I. N. [1 ]
Popov, B. [1 ]
Kantardjiev, T. V. [1 ]
机构
[1] Natl Ctr Infect & Parasit Dis, Dept Microbiol, Sofia 1504, Bulgaria
来源
EPIDEMIOLOGY AND INFECTION | 2010年 / 138卷 / 03期
关键词
Bird-to-human transmission; Francisella tularensis; hunter; MLVA; nail scratch; TULAREMIA; INFECTION;
D O I
10.1017/S0950268809990513
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
During a recent large tularemia outbreak in Bulgaria we found several cases that were remote from the main focus. One case had an unusual mode of transmission. A hunter acquired tularemia through a nail scratch from a buzzard (Buteo buteo) and consequently developed a typical ulceroglandular form of the disease. The diagnosis was confirmed by serological methods and successful cultivation. Comparative strain typing was performed by high-resolution multi-locus variable-number tandem repeat analysis (MLVA). The isolated strain was identical to one of the outbreak genotypes. We consider that this case represents a bird-to-human transmission of F. tularensis.
引用
收藏
页码:376 / 379
页数:4
相关论文
共 1 条
  • [1] Normal human pituitary gland and pituitary adenomas express cannabinoid receptor type 1 and synthesize endogenous cannabinoids:: First evidence for a direct role of cannabinoids on hormone modulation at the human pituitary level
    Pagotto, U
    Marsicano, G
    Fezza, F
    Theodoropoulou, M
    Grübler, Y
    Stalla, J
    Arzberger, T
    Milone, A
    Losa, M
    Di Marzo, V
    Lutz, B
    Stalla, GK
    [J]. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2001, 86 (06): : 2687 - 2696