The mediating role of depression on the relationship between housebound status and cognitive function among the elderly in rural communities: A cross-sectional study

Objective: To explore the relationship among housebound status, depression and cognitive function, and further to study whether depression can take on a mediator among elders in rural communities. Methods: A cross-sectional survey was conducted among 720 community residents aged >= 60 years from March to May in 2016 in Hebei province, China. We used the Chinese version of Housebound scale, the Rasch-Derived of the Center for Epidemiological studies Depression scale (CES-D-R), and the Minimental State Examination Scale (MMSE) to estimate housebound status, depression, and cognitive function separately. Correlation, multiple linear regression, and structural equation modeling was used to data analyses. Results: 712 completely replied questionnaires were finally used in the data analyses among 720 questionnaires, which indicated that effective response rate was 98.9%. Results indicated that the scores of housebound status were positively correlated with the MMSE scores. Being housebound correlated negatively with MMSE scores. Housebound status and three dimensions of CES-D-R (i.e. negative affect, positive affect, and interpersonal problems) were deemed as significant predictors of cognitive function among rural elders. The effect of housebound status on cognitive function was fully mediated by depression. Conclusions: Not all subscales of CES-D-R can affect MMSE scores among rural elders. There may be full mediation effects of depression within the impact of housebound status on cognitive function, mainly through negative affect, positive affect and interpersonal problems. It indicates that preventing the elderly from housebound status could relieve the decline of cognitive function by the intermediary role of depression.