Reactive hemophagocytic syndrome associated with disseminated histoplasmosis in a heart transplant recipient

被引:29
|
作者
Masri, K
Mahon, N
Rosario, A
Mirza, I
Keys, TF
Ratliff, NB
Starling, RC
机构
[1] Cleveland Clin Fdn, Kaufman Ctr Heart Failure, Sect Heart Failure & Transplant Med, Dept Cardiovasc Med, Cleveland, OH 44195 USA
[2] Cleveland Clin Fdn, Dept Pathol, Cleveland, OH 44195 USA
[3] Cleveland Clin Fdn, Dept Infect Dis, Cleveland, OH 44195 USA
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关键词
D O I
10.1016/S1053-2498(02)00817-3
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
We describe a patient who developed multi-organ failure with reactive hemophagocytic syndrome secondary to disseminated histoplasmosis 8 months after orthotopic heart, transplantation. The patient responded fully to a prolonged course of therapy with amphotericin B and remains free of recurrence. Disseminated histoplasmosis and reactive hemophagocytic syndrome have rarely been described in the setting of cardiac transplantation and never before in combination.
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收藏
页码:487 / 491
页数:5
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