The use of human sewage screening for community surveillance of hepatitis E virus in the UK

被引：34
|
作者：
Smith, Donald B. [1 ]
Paddy, Julius O. [2 ]
Simmonds, Peter [2 ]
机构：
[1] Univ Edinburgh, CIIE, Ashworth Labs, Kings Bldg, Edinburgh EH9 3FL, Midlothian, Scotland
[2] Univ Edinburgh, Roslin Inst, Edinburgh EH9 3FL, Midlothian, Scotland
来源：
JOURNAL OF MEDICAL VIROLOGY | 2016年 / 88卷 / 05期
基金：
英国生物技术与生命科学研究理事会; 英国惠康基金;
关键词：
epidemiology; variation; detection; WASTE-WATER; INFECTION; SAMPLES; PLANTS; RAW;
D O I：
10.1002/jmv.24403
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Hepatitis E virus sequences were detected by RT-PCR in 14/15 (93%) of untreated sewage samples from Edinburgh, Scotland, UK. Phylogenetic analysis of amplicons at limiting dilution revealed the co-circulation of multiple variants of HEV-3, with a pattern of diversity matching that observed in a local cohort of HEV-infected hepatitis patients. J. Med. Virol. 88:915-918, 2016. (c) 2015 The Authors. Journal of Medical Virology Published by Wiley Periodicals, Inc.
引用
收藏
页码：915 / 918
页数：4
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