Early Safety Monitoring of COVID-19 Vaccines in Healthcare Workers

被引：20
|
作者：
Song, Joon Young [1 ,2 ]
Cheong, Hee Jin [1 ,2 ]
Kim, Sung Ran [2 ]
Lee, Sung Eun [3 ]
Kim, Su Hyun [4 ]
Noh, Ji Yun [1 ,2 ]
Yoon, Young Kyung [3 ,5 ]
Choi, Won Suk [4 ,6 ]
Park, Dae Won [4 ,6 ]
Sohn, Jang Wook [3 ,5 ]
Kim, Woo Joo [1 ,2 ]
Kim, Min Ja [3 ,5 ]
机构：
[1] Korea Univ, Coll Med, Dept Internal Med, Div Infect Dis,Guro Hosp, 148 Gurodong Ro, Seoul 08308, South Korea
[2] Korea Univ, Dept Hosp Infect Control, Guro Hosp, Seoul, South Korea
[3] Korea Univ, Dept Hosp Infect Control, Anam Hosp, Seoul, South Korea
[4] Korea Univ, Dept Hosp Infect Control, Ansan Hosp, Ansan, South Korea
[5] Korea Univ, Coll Med, Dept Internal Med, Div Infect Dis,Anam Hosp, Seoul, South Korea
[6] Korea Univ, Coll Med, Dept Internal Med, Div Infect Dis,Ansan Hosp, Ansan, South Korea
来源：
JOURNAL OF KOREAN MEDICAL SCIENCE | 2021年 / 36卷 / 15期
关键词：
COVID-19; Vaccine; Safety; Adverse Event; Surveillance;
D O I：
10.3346/jkms.2021.36.e110
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Hospital-based surveillance for adverse events was conducted on healthcare workers after they received the first dose of coronavirus disease 2019 (COVID-19) vaccine. Among the two new platform vaccines (messenger RNA- and adenoviral vector-based vaccines), the rates of systemic adverse events were significantly higher among adenovirus-vectored vaccine recipients. Fatigue (87.6% vs. 53.8%), myalgia (80.8% vs. 50.0%), headache (72.0% vs. 28.8%), and fever (>= 38.0 degrees C, 38.7% vs. 0%) were the most common adverse events among adenovirus-vectored vaccine recipients, but most symptoms resolved within 2 days. Both types of COVID-19 vaccines were generally safe, and serious adverse events rarely occurred.
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页数：4
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