Recent Advances in the Detection of Methicillin Resistant Staphylococcus aureus (MRSA)

被引:25
|
作者
Hulme, John [1 ,2 ]
机构
[1] Gachon Univ, Dept Bionano Technol, 1342 Sungnam Daero, Seongnam Si 13120, Gyeonggi, South Korea
[2] Gachon Univ, Gachon Med Res Inst, 1342 Sungnam Daero, Seongnam Si 13120, Gyeonggi, South Korea
关键词
Automated; Microfluidic; Point of care; Digital; Mass spectrometry; POSITIVE BLOOD CULTURES; MASS-SPECTROMETRY; CLINICAL MICROBIOLOGY; IMMUNOCHROMATOGRAPHIC ASSAY; ELECTROCHEMICAL DETECTION; SENSITIVE DETECTION; RAPID DETECTION; S; AUREUS; PCR ASSAY; IDENTIFICATION;
D O I
10.1007/s13206-016-1201-9
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
According to the World Health Organization (WHO) 20% of all documented S. aureus infections are attributable to MRSA, although for some developing countries this value can exceed 80%. Thus the rapid and accurate detection of MRSA in low resource settings (LDR) is becoming essential. Yet conventional microbial detection methods take from 1-5 days to identify MRSA. Recently, new types of automated laboratory methods as well as advances in nucleic acid testing, microfluidic technology, immunosensors, biosensors and point of care testing have reduced the time to detection to <1 hr. This review examines the current limitations and advances in methodologies employed in the rapid detection of MRSA.
引用
收藏
页码:89 / 100
页数:12
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