Cellular mechanisms of laser phototherapy

被引：0
|
作者：
Karu, T. I. [1 ]
机构：
[1] Russian Acad Sci, Inst Laser & Informat Technol, Troitsk, Moscow Region, Russia
来源：
PROCEEDINGS OF THE 6TH INTERNATIONAL CONGRESS OF THE WORLD ASSOCIATION OF LASER THERAPY | 2006年
关键词：
D O I：
暂无
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
1. The terminal enzyme of mitochondrial respiratory chain cytochrome c oxidase is considered as a universal photoacceptor in mammalian cells for visible-to-near IR radiation. 2. Two mechanisms occurring in cytochrome c oxidase under irradiation are investigated experimentally. These are an increase of electron flow inside of cytochrome c oxidase and a relieve of NO block in the catalytic center of cytochrome c oxidase. 3. A novel mitochondrial light-activated cellular signaling pathway have been discovered and investigated. 4. Our results evidence that cytochrome c oxidase can work as a signal generator as well as a signal transducer in irradiated cells.
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页码：27 / 31
页数：5
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