Prognosis and transition of multi-site pain during the course of 5 years: Results of knee pain and function from a prospective cohort study among 756 adolescents

被引:7
|
作者
Holden, Sinead [1 ,2 ]
Roos, Ewa M. [3 ]
Straszek, Christian Lund [1 ]
Olesen, Jens Lykkegaard [1 ,4 ]
Jensen, Martin Bach [1 ]
Graven-Nielsen, Thomas [5 ]
Rathleff, Michael Skovdal [1 ,2 ,4 ]
机构
[1] Aalborg Univ, Ctr Gen Practice, Aalborg, Denmark
[2] Aalborg Univ, Dept Hlth Sci & Technol, Aalborg, Denmark
[3] Univ Southern Denmark, Inst Sports Sci & Clin Biomechan, Res Unit Musculoskeletal Funct & Physiotherapy, Odense, Denmark
[4] Copenhagen Univ Hosp, Inst Sports Med Copenhagen, Bispebjerg, Denmark
[5] Aalborg Univ, Ctr Neuroplast & Pain CNAP SMI, Dept Hlth Sci & Technol, Aalborg, Denmark
来源
PLOS ONE | 2021年 / 16卷 / 05期
关键词
MUSCULOSKELETAL PAIN; WIDESPREAD PAIN; SCHOOL-CHILDREN; EARLY ADULTHOOD; RISK-FACTORS; POPULATION; HEALTH; CHILDHOOD;
D O I
10.1371/journal.pone.0250415
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Introduction Multi-site pain has not been investigated among adolescents suffering from knee pain. This study aimed to examine the trajectory of pain in adolescents with knee-pain, to determine if multi-site pain in adolescents together with other established prognostic factors (frequency of pain, sex, sports participation, Health Related Quality of Life (HRQoL)) was associated with five-year prognosis of knee-pain and function. Methods This prospective cohort study included 504 adolescents with knee pain and 252 controls. At five-year follow-up, participants responded to an questionnaire which documented prescence and severity of knee pain and co-occurring pain. Results At follow-up, 358 (71.0%) of those with knee-pain at baseline, and 182 (72.2%) controls responded. Female sex, low HRQoL, daily pain, and multi-site pain were associated with an increased odds of knee pain after 5 years (odds ratio: 1.41-3.37). Baseline multi-site pain was not associated with problems running at follow-up, whereas higher sports participation at baseline was associated with less problems running at follow-up (odd ratio 0.49). Among those with knee-pain at inclusion, the number of pain sites increased from a median of 2 (IQR 1-3) to 4 (IQR 2-6) at follow-up (P<0.05). Those with multi-site pain at follow-up score significantly worse in self-reported knee function, compared to those with one pain site only. Conclusion This study identified a set of factors that appeared to be associated with an increased risk of knee pain at five years follow up. Research is needed to understand and help direct treatment of adolescents with multi-site pain.
引用
收藏
页数:12
相关论文
共 41 条
  • [1] Multi-site chronic pain and cognitive performance: a prospective cohort study in the UK Biobank
    Kelleher, E.
    Schrepf, A.
    Tracey, I.
    Soni, A.
    BRITISH JOURNAL OF ANAESTHESIA, 2023, 131 (03) : E83 - E84
  • [2] DETERMINANTS OF TRAJECTORIES OF MULTI-SITE PAIN IN KNEE OSTEOARTHRITIS: A 10.7-YEAR PROSPECTIVE STUDY IN OLDER ADULTS
    Pan, F.
    Tian, J.
    Cicuttini, F.
    Ding, C.
    Jones, G.
    ANNALS OF THE RHEUMATIC DISEASES, 2018, 77 : 1195 - 1195
  • [3] Disabling knee pain - another consequence of obesity: Results from a prospective cohort study
    Jinks, Clare
    Jordan, Kelvin
    Croft, Peter
    BMC PUBLIC HEALTH, 2006, 6 (1)
  • [4] Disabling knee pain – another consequence of obesity: Results from a prospective cohort study
    Clare Jinks
    Kelvin Jordan
    Peter Croft
    BMC Public Health, 6
  • [5] Sleep as a predictive factor for the onset and resolution of multi-site pain: A 5-year prospective study
    Aili, K.
    Nyman, T.
    Svartengren, M.
    Hillert, L.
    EUROPEAN JOURNAL OF PAIN, 2015, 19 (03) : 341 - 349
  • [6] Five-year prognosis and impact of adolescent knee pain: a prospective population-based cohort study of 504 adolescents in Denmark
    Rathleff, Michael Skovdal
    Holden, Sinead
    Straszek, Christian Lund
    Olesen, Jens Lykkegaard
    Jensen, Martin Bach
    Roos, Ewa M.
    BMJ OPEN, 2019, 9 (05):
  • [7] Research Among Women Sexual Assault Survivors Presenting for Emergency Care is Justified: Results From a Multi-Site, Prospective Observational Cohort Study
    Burud, Grace
    Short, Nicole A.
    Thomas, Riya
    Lechner, Megan
    Bell, Kathy
    Black, Jenny
    Buchanan, Jennie
    Reese, Rhiannon
    Ho, Jeffrey
    Reed, Gordon
    Platt, Melissa
    Riviello, Ralph
    Rossi, Catherine
    Nouhan, Patricia
    Phillips, Carolyn
    Martin, Sandra L.
    Liberzon, Israel
    Rauch, Sheila A. M.
    Bollen, Kenneth
    Kessler, Ronald C.
    McLean, Samuel
    BIOLOGICAL PSYCHIATRY, 2021, 89 (09) : S158 - S158
  • [8] Knee Pain During the First Three Months After Unilateral Total Knee Arthroplasty A Multi-Centre Prospective Cohort Study
    Morze, Conrad J.
    Johnson, Nigel R.
    Williams, Gail
    Moroney, Mark
    Lamberton, Tony
    McAuliffe, Michael
    JOURNAL OF ARTHROPLASTY, 2013, 28 (09): : 1565 - 1570
  • [9] Defining knee pain trajectories in early symptomatic knee osteoarthritis in primary care: 5-year results from a nationwide prospective cohort study (CHECK)
    Bastick, Alex N.
    Wesseling, Janet
    Damen, Jurgen
    Verkleij, Saskia P. J.
    Emans, Pieter J.
    Bindels, Patrick J. E.
    Bierma-Zeinstra, Sita M. A.
    BRITISH JOURNAL OF GENERAL PRACTICE, 2016, 66 (642): : E32 - E39
  • [10] Preoperative measures of pain at rest and movement-evoked pain in knee arthroplasty: Associations with pain and function outcome trajectories from a prospective multicentre longitudinal cohort study
    Riddle, Daniel L.
    Dumenci, Levent
    EUROPEAN JOURNAL OF PAIN, 2025, 29 (02)