Effect of Cytokines on the Formation Tube-Like Structures by Endothelial Cells in the Presence of Trophoblast Cells

被引：11
|
作者：
Sokolov, D. I. [1 ]
Lvova, T. Yu. [1 ]
Okorokova, L. S. [1 ]
Belyakova, K. L. [1 ]
Sheveleva, A. R. [1 ]
Stepanova, O. I. [1 ]
Mikhailova, V. A. [1 ]
Sel'kov, S. A. [1 ]
机构：
[1] DO Ott Res Inst Obstet & Gynecol, St Petersburg, Russia
来源：
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2017年 / 163卷 / 01期
关键词：
endothelium; trophoblast; cytokines; angiogenesis; placenta; NECROSIS-FACTOR-ALPHA; MATERNAL-FETAL INTERFACE; HUMAN PLACENTA; GROWTH-FACTOR; IN-VITRO; EXTRAVILLOUS TROPHOBLAST; INTERFERON-GAMMA; MATRIX METALLOPROTEINASES; PREECLAMPTIC PREGNANCIES; MESSENGER-RNA;
D O I：
10.1007/s10517-017-3756-4
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Despite ample data on cytokine secretion in the uteroplacental interface, the influence of microenvironment cells, in particular, trophoblast cells on angiogenesis and the role of cytokines in this process remain poorly studied. We studied the influence of cytokines on the formation of tube-like structures by endothelial cells in the presence of trophoblast cells and showed that trophoblast cells suppressed the angiogenic potential of endothelial cells. Antiangiogenic cytokines IFN-gamma, IL-10, TNF-alpha, and TGF beta via modulation of trophoblast cells stimulated the formation of tube-like structures by endothelial cells. In the co-culture of endothelial and trophoblast cells, the effects of cytokines changed and they gained additional regulatory functions.
引用
下载
收藏
页码：148 / 158
页数：11
相关论文
共 50 条
  • [1] Effect of Cytokines on the Formation Tube-Like Structures by Endothelial Cells in the Presence of Trophoblast Cells
    D. I. Sokolov
    T. Yu. Lvova
    L. S. Okorokova
    K. L. Belyakova
    A. R. Sheveleva
    O. I. Stepanova
    V. A. Mikhailova
    S. A. Sel’kov
    Bulletin of Experimental Biology and Medicine, 2017, 163 : 148 - 158
  • [2] Effects of antiretroviral therapy on tube-like network formation of human endothelial cells
    Di Simone, Nicoletta
    De Santis, Marco
    Tamburrin, Enrica
    Di Nicuolo, Fiorella
    Lucia, Mothanje Barbara
    Riccardi, Patrizia
    D'Ippolito, Silvia
    Cauda, Roberto
    Caruso, Alessandro
    BIOLOGICAL & PHARMACEUTICAL BULLETIN, 2007, 30 (05) : 982 - 984
  • [3] Microchannel Molding Combined with Layer-by-Layer Approach for the Formation of Three-Dimensional Tube-like Structures by Endothelial Cells
    Aor, Bruno
    Khan, Irfan
    Glinel, Karine
    Jonas, Alain M.
    Demoustier-Champagne, Sophie
    Durrieu, Marie-Christine
    ACS APPLIED BIO MATERIALS, 2020, 3 (03) : 1520 - 1532
  • [4] Novel biological functions of interleukin-4:: Formation of tube-like structures by vascular endothelial cells in vitro and angiogenesis in vivo
    Fukushi, J
    Morisaki, T
    Shono, T
    Nishie, A
    Torisu, H
    Ono, M
    Kuwano, M
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1998, 250 (02) : 444 - 448
  • [5] Induction of apoptosis and inhibition of cell migration and tube-like formation by dihydroartemisinin in murine lymphatic endothelial cells
    Wang, Jun
    Guo, Yan
    Zhang, Bi-Cheng
    Chen, Zheng-Tang
    Gao, Jian-Fei
    PHARMACOLOGY, 2007, 80 (04) : 207 - 218
  • [6] Formation of capillary tube-like structures on micropatterned biomaterials
    Gao, Dahai
    Kumar, Girish
    Co, Carlos
    Ho, Chia-Chi
    OXYGEN TRANSPORT TO TISSUE XXIX, 2008, 614 : 199 - 205
  • [7] Inhibitory effect of Adonis amurensis components on tube-like formation of human umbilical venous cells
    You, YJ
    Kim, Y
    Nam, NH
    Ahn, BZ
    PHYTOTHERAPY RESEARCH, 2003, 17 (05) : 568 - 570
  • [8] Involvement of integrin-linked kinase in capillary/tube-like network formation of human vascular endothelial cells
    Motomu Watanabe
    Yayoi Fujioka-Kaneko
    Hisayuki Kobayashi
    Mamoru Kiniwa
    Michihiko Kuwano
    Yuji Basaki
    Biological Procedures Online, 2005, 7 : 41 - 47
  • [9] Involvement of integrin-linked kinase in capillary/tube-like network formation of human vascular endothelial cells
    Watanabe, M
    Fujioka-Kaneko, Y
    Kobayashi, H
    Kiniwa, M
    Kuwano, M
    Basaki, Y
    BIOLOGICAL PROCEDURES ONLINE, 2005, 7 (1) : 41 - 47
  • [10] THE EFFECTS OF VARIOUS GROWTH-FACTORS ON TUBE-LIKE STRUCTURES OF RAT SINUSOIDAL ENDOTHELIAL-CELLS CULTURED ON MATRIGEL
    SHAKADO, S
    SAKISAKA, S
    NOGUCHI, K
    OHISHI, M
    HARADA, M
    MIMURA, Y
    SATA, M
    TANIKAWA, K
    HEPATOLOGY, 1994, 20 (04) : A211 - A211
12345