Phytochemical Analysis, Antioxidant and Anti-Inflammatory Activity of Calyces from Physalis peruviana

被引：0

作者：

Toro, Reina M. ^{[1
]}

Aragon, Diana M. ^{[1
]}

Ospina, Luis F. ^{[1
]}

Ramos, Freddy A. ^{[2
]}

Castellanos, Leonardo ^{[2
]}

机构：

[1] Univ Nacl Colombia, Dept Farm, Bogota, Colombia

[2] Univ Nacl Colombia, Dept Quim, Bogota, Colombia

来源：

NATURAL PRODUCT COMMUNICATIONS | 2014年 / 9卷 / 11期

关键词：

Antioxidant; Anti-inflammatory; Physalis peruviana; Rutin; Nicotoflorin; RUTIN; FLAVONOIDS; EXTRACT;

D O I：

暂无

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Physalis peruviana calyces are used extensively in folk medicine. The crude ethanolic extract and some fractions of calyces were evaluated in order to explore antioxidant and anti-inflammatory activities. The anti-inflammatory activity was evaluated by the TPA-induced ear edema model. The antioxidant in vitro activity was measured by means of the superoxide and nitric oxide scavenging activity of the extracts and fractions. The butanolic fraction was found to be promising due to its anti-inflammatory and antioxidant activities.Therefore, a bio-assay guided approach was employed to isolate and identify rutin (1) and nicotoflorin (2) from their NMR spectroscopic and MS data. The identification of rutin in calyces of P. peruviana supports the possible use of this waste material for phytotherapeutic, nutraceutical and cosmetic preparations.

引用

页码：1573 / 1575

页数：3

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