Texture medical image classification is a major task in many areas of computer vision and pattern recognition, including biomedical imaging. In reality, optical surfaces can be abused to recognize particular tissues or cells in a true example, to feature complex chemical reactions between molecules, and additionally to identify subcellular designs that can be confirmation of specific pathologies. It makes automated texture analysis fundamental in many applications of biomedicine, such as the accurate detection and grading of multiple types of cancer, the differential diagnosis of autoimmune diseases, or the study of physiological processes. Due to their specific characteristics and challenges, the design of texture analysis systems for biological images has attracted ever-growing attention in the last few years. In this work, approach applies the multi-scale gabor rotation-invariant local binary pattern (MGRLBP) used to analysis the texture features of a bio medicinal image and joined the weight aspect that is presented by the direct measure to obtain the last texture feature of a biomedical picture. By using multi-scale binary pattern (MSBP) classifier with the direct action and multi-scale gabor rotation-invariant local binary pattern algorithm. Both quantitative and qualitative methods are applied to assess the classification results. The simulation work does with the MATLAB2013a environment by using proposed MGRLBP and MSBP technique. The simulation results demonstrate the usefulness of the suggested technique and its ability to classify the texture medical images. Hence the proposed model produces better features for texture in medical images. Over 93% efficiency achieved by using MGRLBP and MSBP method.