DROPLET DIGITAL PCR IS A SENSITIVE TOOL FOR DETECTION OF TP53 DELETIONS AND POINT MUTATIONS IN CHRONIC LYMPHOCYTIC LEUKEMIA

被引:0
|
作者
Frazzi, R. [1 ]
Bizzarri, V. [2 ]
Albertazzi, L. [3 ]
Cusenza, V. Y. [1 ]
Coppolecchia, L. [4 ]
Luminari, S. [4 ]
Ilariucci, F. [4 ]
机构
[1] Azienda Unita Sanit Locale IRCCS Reggio Emilia, Lab Translat Res, Reggio Emilia, Italy
[2] Azienda Unita Sanit Locale IRCCS Reggio Emilia, Genet Lab, Reggio Emilia, Italy
[3] Azienda Unita Sanit Locale IRCCS Reggio Emilia, Lab Chem Chem, Reggio Emilia, Italy
[4] Azienda Unita Sanit Locale IRCCS Reggio Emilia, Hematol, Reggio Emilia, Italy
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
P105
引用
收藏
页码:100 / 100
页数:1
相关论文
共 50 条
  • [1] Droplet digital PCR is a sensitive tool for the detection of TP53 deletions and point mutations in chronic lymphocytic leukaemia
    Frazzi, Raffaele
    Bizzarri, Veronica
    Albertazzi, Laura
    Cusenza, Vincenza Ylenia
    Coppolecchia, Lia
    Luminari, Stefano
    Ilariucci, Fiorella
    [J]. BRITISH JOURNAL OF HAEMATOLOGY, 2020, 189 (02) : E49 - E52
  • [2] The TP53 Codon72 Polymorphism Is Associated with TP53 Mutations in Chronic Lymphocytic Leukemia
    Grossmann, Vera
    Artusi, Valentina
    Schnittger, Susanne
    Dicker, Frank
    Jeromin, Sabine
    Boeck, Lucia
    Haferlach, Torsten
    Haferlach, Claudia
    Kern, Wolfgang
    Kohlmann, Alexander
    [J]. BLOOD, 2011, 118 (21) : 778 - 778
  • [3] Detection of somatic TP53 mutations and 17p deletions in patients with chronic lymphocytic leukemia: a review of the current methods
    Chauffaille, Maria de Lourdes L. F.
    Zalcberg, Ilana
    Barrero, Wolney Gois
    Bendit, Israel
    [J]. HEMATOLOGY TRANSFUSION AND CELL THERAPY, 2020, 42 (03) : 261 - 268
  • [4] Selection of new TP53 mutations by therapy in chronic lymphocytic leukemia
    Trbusek, Martin
    Malcikova, Jitka
    Mayer, Jiri
    [J]. LEUKEMIA RESEARCH, 2011, 35 (07) : 981 - 982
  • [5] TP53 Mutations are infrequent in newly diagnosed chronic lymphocytic leukemia
    Zainuddin, Norafiza
    Murray, Fiona
    Kanduri, Meena
    Gunnarsson, Rebeqa
    Smedby, Karin E.
    Enblad, Gunilla
    Jurlander, Jesper
    Juliusson, Gunnar
    Rosenquist, Richard
    [J]. LEUKEMIA RESEARCH, 2011, 35 (02) : 272 - 274
  • [6] Clinical Impact of Clonal and Subclonal TP53 Mutations and Deletions in Chronic Lymphocytic Leukemia: An Italian Multicenter Experience
    Bomben, Riccardo
    Rossi, Francesca Maria
    D'Agaro, Tiziana
    Bittolo, Tamara
    Vit, Filippo
    Zucchetto, Antonella
    Tissino, Erika
    Pozzo, Federico
    Ballerini, Mario
    Bulian, Pietro
    Degan, Massimo
    Polesel, Jerry
    Zaina, Eva
    Cattarossi, Ilaria
    Nanni, Paola
    Chivilo, Hillarj
    D'Arena, Giovanni Francesco
    Santinelli, Enrico
    Biagi, Annalisa
    Chiarenza, Annalisa
    Zaja, Francesco
    Pozzato, Gabriele
    Di Raimondo, Francesco
    Rossi, Davide
    Del Poeta, Giovanni
    Gattei, Valter
    [J]. BLOOD, 2019, 134
  • [7] Clinical impact of clonal and subclonal TP53 mutations and deletions in chronic lymphocytic leukemia: an Italian multicenter experience
    Bomben, Riccardo
    Rossi, Francesca Maria
    D'Agaro, Tiziana
    Bittolo, Tamara
    Vit, Filippo
    Zucchetto, Antonella
    Tissino, Erika
    Pozzo, Federico
    Bulian, Pietro
    Degan, Massimo
    Polesel, Jerry
    D'Arena, Giovanni
    Santinelli, Enrico
    Biagi, Annalisa
    Chiarenza, Annalisa
    Zaja, Francesco
    Pozzato, Gabriele
    Di Raimondo, Francesco
    Rossi, Davide
    Del Poeta, Giovanni
    Gattei, Valter
    [J]. LEUKEMIA & LYMPHOMA, 2020, 61 : 215 - 217
  • [8] TP53 Aberrations in Chronic Lymphocytic Leukemia
    Trbusek, Martin
    Malcikova, Jitka
    [J]. ADVANCES IN CHRONIC LYMPHOCYTIC LEUKEMIA, 2013, 792 : 109 - 131
  • [9] Prognostic significance of ATM and TP53 deletions in Chinese patients with chronic lymphocytic leukemia
    Xu, Wei
    Li, Jian-Yong
    Wu, Yu-Jie
    Yu, Hui
    Shen, Qiu-Dan
    Li, Li
    Fan, Lei
    Qiu, Hong-Xia
    [J]. LEUKEMIA RESEARCH, 2008, 32 (07) : 1071 - 1077
  • [10] Clinical Impact of Clonal and Subclonal TP53 Mutations in Chronic Lymphocytic Leukemia
    Bomben, Riccardo
    Rossi, Maria Francesca
    D'Agaro, Tiziana
    Bittolo, Tamara
    Zucchetto, Antonella
    Tissino, Erika
    Pozzo, Federico
    Vit, Filippo
    Bulian, Pietro
    Degan, Massimo
    Zaina, Eva
    Cattarossi, Ilaria
    Nanni, Paola
    Chivilo, Hillarj
    D'Arena, Giovanni Francesco
    Chiarenza, Annalisa
    Santinelli, Enrico
    Zaja, Francesco
    Pozzato, Gabriele
    Di Raimondo, Francesco
    Del Poeta, Giovanni
    Gattei, Valter
    [J]. BLOOD, 2018, 132