Synthesis of (3R,5R)-harzialactone A and its (3R,5S)-isomer

被引：9
|
作者：
Sabitha, Gowravaram [1 ]
Srinivas, Rangavajjula [1 ]
Das, Sukant K. [1 ]
Yadav, Jhillu S. [1 ]
机构：
[1] Indian Inst Chem Technol, Organ Div 1, Hyderabad 500007, Andhra Pradesh, India
来源：
BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY | 2010年 / 6卷
关键词：
dithiane; harzialactone A; hydroxyl directed reduction; stereoisomer; ABSOLUTE STEREOCHEMISTRY; DIRECTED REDUCTION; HARZIALACTONE-A; GALANTINIC ACID; D-GLUCOSE; ESTER;
D O I：
10.3762/bjoc.6.8
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The total synthesis of (3R,5R)-harzialactone A (1) and its (3R,5S)-isomer (2) is described. Epoxide opening with thioacetal and diastereoselective reductions are used as key reactions.
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页数：3
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