Convergent synthesis of the C31-C46 domain of the phorboxazole natural products

被引：47
|
作者：
Ahmed, F [1 ]
Forsyth, CJ [1 ]
机构：
[1] Univ Minnesota, Dept Chem, Minneapolis, MN 55455 USA
来源：
TETRAHEDRON LETTERS | 1998年 / 39卷 / 3-4期
关键词：
D O I：
10.1016/S0040-4039(97)10519-6
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A convergent synthesis of the C31-C46 domain of the phorboxazole natural products has been developed. This involved the preparation of a C39-C46 dienyl iodide and a C31-C37 aldehyde, followed by their CrCl2-mediated coupling and final installation of the C46 (E)-vinyl bromide via an alkyne hydrostannation-bromination sequence. (C) 1997 Elsevier Science Ltd. All rights reserved.
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收藏
页码：183 / 186
页数：4
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