Pre-Clinical Activity of Adct-301, a Novel Pyrrolobenzodiazepine (PBD) Dimer-Containing Antibody Drug Conjugate (ADC) Targeting CD25-Expressing Hematological Malignancies

被引：6
|
作者：
Flynn, Michael J. [1 ,2 ]
van Berkel, Patrick [3 ]
Zammarchi, Francesca [3 ]
Levy, Jean-Noel [2 ]
Tiberghien, Arnaud [2 ]
Masterson, Luke A. [2 ]
D'Hooge, Francois [2 ]
Adams, Lauren [2 ]
Williams, David G. [2 ]
Howard, Philip W. [2 ,3 ]
Hartley, John A. [1 ,2 ,3 ]
机构：
[1] UCL, London, England
[2] Medimmune, Cambridge, England
[3] ADC Therapeut Sarl, Epalinges, Switzerland
来源：
BLOOD | 2014年 / 124卷 / 21期
关键词：
D O I：
10.1182/blood.V124.21.4491.4491
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页数：3
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    Hartley, John A.
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    Shende, Vishvesh
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    [J]. BLOOD, 2015, 126 (23)
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    [J]. BLOOD, 2015, 126 (23)
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    [J]. CANCER RESEARCH, 2017, 77
  • [7] Preclinical activity of ADCT-601, a novel pyrrolobenzodiazepine (PBD) dimer-based antibody-drug conjugate (ADC) targeting AXL-expressing tumors
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    [J]. CANCER RESEARCH, 2018, 78 (13)
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    [J]. MOLECULAR CANCER THERAPEUTICS, 2024, 23 (04) : 520 - 531
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    [J]. EUROPEAN JOURNAL OF CANCER, 2016, 69 : S28 - S28
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