To indentify correlations between burnout and Big Five dimensions among residents in obstetrics and gynecology. Methods: a total of 41% of all residents from this medical specialty from a university centre in North-eastern Romania answered to two scales (Big Five Inventory and Maslach Burnout Inventory). The objective was to identify the relation between five factor model of personality and burnout syndrome. Variables like age, gender, marital status, working hours, number of swifts, and some other psychological data were considered. Data were analyzed using SPSS 17.0. Results: More than 3/4 of the subjects working in obstetrics and gynecology are women with an average of M = 27.7 +/- 2, 15. Almost one third (30.77%) is involved in a relationship, 33.33% (N = 13) are married and 35.90% (N = 14) are single. Number of working hours is showing an M = 54.29 +/- 17.79 and number of swifts per month has an M = 5.20 +/- 1.65. Descriptive, correlational and comparative analyses are presented in the research. Emotional exhaustion, openness and conscientiousness are positively correlated with burnout. Conclusions: Most of the residents are associating burnout with emotional exhausting. Number of working hours, number of swifts per month, extraversion, neuroticism, openness and neuroticism are having important effects on burnout level. Results regarding sleep troubles, depression and use of drugs among residents are detailed in the paper. Because depressive antecedents and insomnia have been mentioned by over one-third of the resident physicians, a thorough research should lead to identifying coping strategies, finding ways to decrease the level of burnout and a psychological education for physicians, during their years of professional training.