High-Resolution CT Findings of Obstructive and Restrictive Phenotypes of Chronic Lung Allograft Dysfunction: More Than Just Bronchiolitis Obliterans Syndrome

被引：20
|
作者：
Hota, Partha [1 ]
Dass, Chandra [1 ]
Kumaran, Maruti [1 ]
Simpson, Scott [1 ]
机构：
[1] Temple Univ Hosp & Med Sch, Dept Radiol, Div Cardiothorac Imaging, 3401 N Broad St, Philadelphia, PA 19140 USA
来源：
AMERICAN JOURNAL OF ROENTGENOLOGY | 2018年 / 211卷 / 01期
关键词：
azithromycin-reversible allograft dysfunction; bronchiolitis obliterans syndrome; chronic lung allograft dysfunction; chronic rejection; high-resolution CT; lung transplantation; restrictive allograft syndrome; HEMATOPOIETIC STEM-CELL; COLLAGEN TYPE-V; FIBRINOID ORGANIZING PNEUMONIA; PRIMARY GRAFT DYSFUNCTION; THIN-SECTION CT; RISK-FACTORS; PLEUROPARENCHYMAL FIBROELASTOSIS; TRANSPLANT RECIPIENTS; CLINICAL-PRACTICE; AZITHROMYCIN;
D O I：
10.2214/AJR.17.19041
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
OBJECTIVE. The purpose of this article is to review the high-resolution CT characteristics of individual obstructive and restrictive chronic lung allograft dysfunction (CLAD) phenotypes to aid in making accurate diagnoses and guiding treatment. CONCLUSION. Long-term survival and function after lung transplant are considerably worse compared with after other organ transplants. CLAD is implicated as a major limiting factor for long-term graft viability. Historically thought to be a single entity, bronchiolitis obliterans syndrome, CLAD is actually a heterogeneous group of disorders with distinct subtypes.
引用
收藏
页码：W13 / W21
页数：9
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