The use of automated solid-phase microextraction (SPME) for permeation studies on substance mixtures and products

The use of solid-phase microextraction for permeation measurements enables a broad spectrum of organic substances to be recovered from different collecting media. In combination with a GC/MS system, it can also be used to separate and identify the substances in substance mixtures and products. The permeation of substances can thus be studied with consideration for the influence of other substances found in the product. Besides the selective search for and analysis of specific substances, a sensitive, non-predictive screening process is also described. With this process, the permeation of substances within products, reaction products and substances from the personal protective equipment (PPE) which are as yet unknown can also be presented, without specification of the substances under analysis.