Retinal phantom applicable to OCT, OCT-angiography, and fundus angiography

The retinal imaging system, such as optical coherence tomography (OCT), OCT-angiography (OCTA) and fluorescein angiography (FA), is the important subject for ophthalmic The use of such equipment continues to increase and retinal phantoms have also been developed to evaluate and modify its performance and image quality. In this presentation, we will show methods and results of a retinal phantom that can evaluate the optical performance of OCT, OCTA and FA. We implemented superficial vascular networks and full retinal layers which has curvature. The retinal phantom was made from a polydimethylsiloxzne (PDMS) mixture with different titanium dioxide (TiO2) concentrations. It was formed by combining two microfluidic channels, two multi-layered thin films and base plate with retinal curvature. We could obtain cross-sectional OCT images and en-face OCTA images using lab-made OCT system. In addition, FA image could also be obtained through sodium fluorescein dye injection.