Serum protein alterations in dogs naturally infected with Toxoplasma gondii

被引:4
|
作者
Yarim, Gul Fatma [1 ]
Nisbet, Cevat
Oncel, Taraneh
Cenesiz, Sena
Ciftci, Gulay
机构
[1] Ondokuz Mayis Univ, Fac Med Vet, Dept Biochem, TR-55139 Kurupelit, Turkey
[2] Vet Control & Res Inst, Dept Parasitol, TR-34890 Istanbul, Turkey
关键词
D O I
10.1007/s00436-007-0601-0
中图分类号
R38 [医学寄生虫学]; Q [生物科学];
学科分类号
07 ; 0710 ; 09 ; 100103 ;
摘要
We conducted this study to describe the serum electrophoretic pattern in dogs associated with the infection of Toxoplasma gondii (T. gondii). The serum protein pattern of 25 dogs with confirmed T. gondii infection and 15 clinically healthy dogs were evaluated using native polyacrylamide gel electrophoresis. Albumin, alpha-1 globulin, alpha-2 globulin, beta globulin, and gamma globulin bands were seen from the serum electrophoresis of infected and healthy dogs. Compared to the control group, significant decreases in the mean percentages of albumin (from 46.1 +/- 7.2 to 40.8 +/- 4.5%, P < 0.05), alpha-1 globulin (from 3.9 +/- 0.4 to 0.8 +/- 0.2%, P < 0.001), alpha-2 globulin (from 9.0 +/- 0.4 to 8.3 +/- 0.8%, P < 0.01), and beta globulin (from 18.4 +/- 1.2 to 12.1 +/- 0.6%, P < 0.001) in the infected group were determined. In contrast, gamma globulin fraction was significantly higher in infected dogs (38.1 +/- 4.6%) than in control dogs (22.7 +/- 7.2%; P < 0.001). Moreover, significant corr-elations were determined between the percentages of the albumin and gamma globulin fractions and liver enzyme tests including aspartate aminotransferase and alanine aminotransferase in infected dogs; however, no correlation was observed for the other protein fractions. In conclusion, marked alterations in serum protein pattern associated with strong modifications of serum protein concentrations are in accordance with the hepatic injury as affirmed by liver enzyme tests that were demonstrated in the canine toxoplasmosis. These findings showed that serum protein electrophoresis can be used in the diagnosis and prognosis of canine toxoplasmosis as a supplementary analysis in combination with serological, clinical, and laboratory findings of this disease.
引用
收藏
页码:1197 / 1202
页数:6
相关论文
共 50 条
  • [1] Serum protein alterations in dogs naturally infected with Toxoplasma gondii
    Gul Fatma Yarim
    Cevat Nisbet
    Taraneh Oncel
    Sena Cenesiz
    Gulay Ciftci
    [J]. Parasitology Research, 2007, 101 : 1197 - 1202
  • [2] Toxoplasma gondii detection in the semen of naturally infected sheep
    Moraes, Erica P. B. X.
    Faria, Eduardo B.
    Batista, Andre M.
    Freitas, Antonio Carlos
    Silva, Jean Carlos R.
    Albuquerque, Pedro Paulo F.
    Mota, Rinaldo A.
    [J]. PESQUISA VETERINARIA BRASILEIRA, 2010, 30 (11): : 915 - 917
  • [3] ISOLATION OF TOXOPLASMA GONDII FROM NATURALLY INFECTED CHICKENS
    FOSTER, BG
    FORREST, RG
    BLANCO, JF
    [J]. TEXAS JOURNAL OF SCIENCE, 1969, 20 (04): : 323 - &
  • [4] Detection and isolation of Toxoplasma gondii from fresh semen of naturally infected dogs in Southern Brazil
    Koch, M. O.
    Weiss, R. R.
    Cruz, A. A.
    Soccol, V. T.
    Goncalves, K. A.
    Bertol, M. A. F.
    Beltrame, O. C.
    Dittrich, R. L.
    [J]. REPRODUCTION IN DOMESTIC ANIMALS, 2016, 51 (04) : 550 - 554
  • [5] Occurrence and genetic characterization of Toxoplasma gondii in naturally infected pigs
    Ľudmila Turčeková
    Daniela Antolová
    Katarína Reiterová
    František Spišák
    [J]. Acta Parasitologica, 2013, 58 : 361 - 366
  • [6] Hyperplastic cholangitis in a naturally Toxoplasma gondii-infected cat
    De Tommasi, Anna S.
    Morini, Maria
    Turba, Maria E.
    Otranto, Domenico
    Bettini, Giuliano
    [J]. VETERINARY QUARTERLY, 2014, 34 (04) : 229 - 231
  • [7] Serum protein alterations in goats naturally infected with Babesia ovis
    Esmaeilnejad, B.
    Tavassoli, M.
    Asri-Rezaei, S.
    Dalir-Naghadeh, B.
    Mardani, K.
    Farhaghpajouh, F.
    Abtahi, S. M.
    [J]. IRANIAN JOURNAL OF VETERINARY RESEARCH, 2013, 14 (02) : 150 - 154
  • [8] Detection of Toxoplasma gondii DNA in the milk of naturally infected ewes
    Camossi, L. G.
    Greca-Junior, H.
    Correa, A. P. F. L.
    Richini-Pereira, V. B.
    Silva, R. C.
    Da Silva, A. V.
    Langoni, H.
    [J]. VETERINARY PARASITOLOGY, 2011, 177 (3-4) : 256 - 261
  • [9] Occurrence and genetic characterization of Toxoplasma gondii in naturally infected pigs
    Turcekova, Ludmila
    Antolova, Daniela
    Reiterova, Katarina
    Spisak, Frantisek
    [J]. ACTA PARASITOLOGICA, 2013, 58 (03) : 361 - 366
  • [10] Immunodetection of Toxoplasma gondii in placenta tissue of naturally infected goats
    Mesquita, E. P.
    Oliveira, J. M. B.
    Silva, G. M.
    Torres, S. M.
    Oliveira, A. A. F.
    Silva Junior, V. A.
    Mota, R. A.
    Amorim, M. J. A. A. L.
    [J]. ARQUIVO BRASILEIRO DE MEDICINA VETERINARIA E ZOOTECNIA, 2019, 71 (01) : 86 - 92