IL-27 regulates HIF-1α-mediated VEGFA response in macrophages of diabetic retinopathy patients and healthy individuals

被引：0
|
作者：
Zhang, Qin [1 ]
Cunha, Andre [1 ]
Li, Shu [2 ]
Hao, Qin [2 ]
Kainz, Vanessa [1 ]
Huang, Qian [1 ]
Wu, Henry [1 ]
机构：
[1] Novartis Inst Biomed Res, OPH, Cambridge, MA USA
[2] Novartis Inst Biomed Res, Biotherapeut & Analyt Technol, Cambridge, MA USA
来源：
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE | 2018年 / 59卷 / 09期
关键词：
D O I：
暂无
中图分类号：
R77 [眼科学];
学科分类号：
100212 ;
摘要：
2515
引用
收藏
页数：3
相关论文
共 30 条
  • [1] IL-27 regulates HIF-1α-mediated VEGFA response in macrophages of diabetic retinopathy patients and healthy individuals
    Zhang, Q.
    da Cunha, A. P.
    Li, S.
    Hao, Q.
    Kainz, V.
    Huang, Q.
    Wu, H. Y.
    CYTOKINE, 2019, 113 : 238 - 247
  • [2] IL-27 signaling negatively regulates FceRI-mediated mast cell activation and allergic response
    Wan, Xiaopeng
    Zhang, Yuanyuan
    Tang, Huanna
    Li, Mengyao
    Jiang, Tianqi
    He, Jia
    Bao, Chunjing
    Wang, Junkai
    Song, Yinjing
    Xiao, Peng
    Liu, Yang
    Lai, Lihua
    Wang, Qingqing
    JOURNAL OF LEUKOCYTE BIOLOGY, 2022, 112 (03) : 411 - 424
  • [3] IFN-α regulates Toll-like receptor-mediated IL-27 gene expression in human macrophages
    Pirhonen, Jaana
    Siren, Jukka
    Julkunen, Iikka
    Matikainen, Sampsa
    JOURNAL OF LEUKOCYTE BIOLOGY, 2007, 82 (05) : 1185 - 1192
  • [4] IFN-α regulates toll-like receptor-mediated IL-27 gene expression in human macrophages
    Pirhonen, J.
    Siren, J.
    Julkunen, I.
    Matikainen, S.
    SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 2007, 65 (06) : 612 - 612
  • [5] The angiogenic response to PLL-g-PEG-mediated HIF-1α plasmid DNA delivery in healthy and diabetic rats
    Thiersch, Markus
    Rimann, Markus
    Panagiotopoulou, Vasiliki
    Oeztuerk, Ece
    Biedermann, Thomas
    Textor, Marcus
    Luehmann, Tessa C.
    Hall, Heike
    BIOMATERIALS, 2013, 34 (16) : 4173 - 4182
  • [6] Epigallocatechin gallate relieves asthmatic symptoms in mice by suppressing HIF-1α/VEGFA-mediated M2 skewing of macrophages
    Yang, Nan
    Li, Xiang
    BIOCHEMICAL PHARMACOLOGY, 2022, 202
  • [7] Inhibition of HIF-1 decreases expression of pro-inflammatory IL-6 and TNF- in diabetic retinopathy
    Gao, Xiuhua
    Li, Yonghua
    Wang, Hongxia
    Li, Chuanbao
    Ding, Jianguang
    ACTA OPHTHALMOLOGICA, 2017, 95 (08) : e746 - e750
  • [8] MEK2 Negatively Regulates Lipopolysaccharide-Mediated IL-1β Production through HIF-1α Expression
    Talwar, Harvinder
    Bouhamdan, Mohamad
    Bauerfeld, Christian
    Talreja, T. Jaya
    Aoidi, Rifdat
    Houde, Nicolas
    Charron, Jean
    Samavati, Lobelia
    JOURNAL OF IMMUNOLOGY, 2019, 202 (06): : 1815 - 1825
  • [9] Neuroglobin regulates hypoxic response of neuronal cells through Hif-1α- and Nrf2-mediated mechanism
    Hota, Kalpana B.
    Hota, Sunil K.
    Srivastava, Ravi B.
    Singh, Shashi B.
    JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 2012, 32 (06): : 1046 - 1060
  • [10] HIF-1 mediated activation of antimicrobial peptide LL-37 in type 2 diabetic patients
    Soumitra Mohanty
    Witchuda Kamolvit
    Silvia Zambrana
    Eduardo Gonzales
    Jonas Tovi
    Kerstin Brismar
    Claes-Göran Östenson
    Annelie Brauner
    Journal of Molecular Medicine, 2022, 100 : 101 - 113
123