Recent Developments in Radiation Oncology: An Overview of Individualised Treatment Strategies in Breast Cancer

被引:16
|
作者
Pazos, Montserrat [1 ]
Schoenecker, Stephan [1 ]
Reitz, Daniel [1 ]
Rogowski, Paul [1 ]
Niyazi, Maximilian [1 ]
Alongi, Filippo [2 ,3 ]
Matuschek, Christiane [4 ]
Braun, Michael [5 ]
Harbeck, Nadia [6 ]
Belka, Claus [1 ]
Corradini, Stefanie [1 ]
机构
[1] Ludwig Maximilians Univ Munchen, Univ Hosp, Dept Radiat Oncol, Marchioninistr 15, D-81377 Munich, Germany
[2] Sacro Cuore Don Calbria Negrar, Dept Radiat Oncol, Verona, Italy
[3] Univ Brescia, Brescia, Italy
[4] Heinrich Heine Univ, Dept Radiat Oncol, Dusseldorf, Germany
[5] Red Cross Hosp, Dept Gynecol & Obstet, Munich, Germany
[6] Ludwig Maximilians Univ Munchen, Univ Hosp, Dept Gynecol & Obstet, Breast Ctr, Munich, Germany
关键词
Breast cancer; Individualised therapy; Hypofractionation; Risk-adapted; REGIONAL NODAL IRRADIATION; RANDOMIZED CLINICAL-TRIAL; ISCHEMIC-HEART-DISEASE; PHASE-II TRIAL; NO BOOST TRIAL; TERM-FOLLOW-UP; CONSERVING SURGERY; INTERNAL MAMMARY; NEOADJUVANT CHEMOTHERAPY; LYMPH-NODES;
D O I
10.1159/000488189
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Radiation therapy (RT) for breast cancer has dramatically changed over the past years, leading to individualized risk-adapted treatment strategies. Historically, the choice of RT regimen was limited to conventional fractionation protocols using standard tangential fields. Nowadays, technological and technical improvements in modern RT have added a variety of other RT modalities, different fractionation schedules, and individualised treatment volumes to the portfolio of breast RT. This review aims to give a short overview on the main topics which have recently found their way into clinical practice: hypofractionated treatment protocols, accelerated partial breast irradiation (APBI) for low-risk patients, deep inspiration breath hold (DIBH) for maximal heart protection, extent of regional nodal irradiation for high-risk patients, and the implementation of new radiation techniques such as intensity modulated RT (IMRT) and volumetric modulated RT (VMAT). (C) 2018 S. Karger GmbH, Freiburg
引用
收藏
页码:285 / 291
页数:7
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