COVID-19 Crisis Creates Opportunity towards Global Monitoring & Surveillance

被引:12
|
作者
Donia, Ahmed [1 ]
Hassan, Sammer-ul [2 ]
Zhang, Xunli [2 ]
Al-Madboly, Lamiaa [3 ]
Bokhari, Habib [1 ]
机构
[1] Comsats Univ Islamabad, Fac Sci, Biosci Dept, Islamabad 45550, Pakistan
[2] Univ Southampton, Fac Engn & Phys Sci, Mech Engn, Southampton SO17 1BJ, Hants, England
[3] Tanta Univ, Fac Pharm, Pharmaceut Microbiol Dept, Tanta 31527, Egypt
来源
PATHOGENS | 2021年 / 10卷 / 03期
关键词
SARS-CoV-2; waterborne pathogens; wastewater surveillance; microbial forensics; next generation monitoring tools; lab-on-a-chip; preparedness; RT-LAMP; PCR; CORONAVIRUS DISEASE 2019; WASTE-WATER; ONE HEALTH; TRANSMISSION; SARS-COV-2; VIRUS; INFECTION; SARS;
D O I
10.3390/pathogens10030256
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The spectrum of emerging new diseases as well as re-emerging old diseases is broadening as infectious agents evolve, adapt, and spread at enormous speeds in response to changing ecosystems. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a recent phenomenon and may take a while to understand its transmission routes from less traveled territories, ranging from fomite exposure routes to wastewater transmission. The critical challenge is how to negotiate with such catastrophic pandemics in high-income countries (HICs similar to 20% of the global population) and low-and middle-income countries (LMICs similar to 80% of the global population) with a total global population size of approximately eight billion, where practical mass testing and tracing is only a remote possibility, particularly in low-and middle-income countries (LMICs). Keeping in mind the population distribution disparities of high-income countries (HICs) and LMICs and urbanisation trends over recent years, traditional wastewater-based surveillance such as that used to combat polio may help in addressing this challenge. The COVID-19 era differs from any previous pandemics or global health challenges in the sense that there is a great deal of curiosity within the global community to find out everything about this virus, ranging from diagnostics, potential vaccines/therapeutics, and possible routes of transmission. In this regard, the fact that the gut is the common niche for both poliovirus and SARS-CoV-2, and due to the shedding of the virus through faecal material into sewerage systems, the need for long-term wastewater surveillance and developing early warning systems for better preparedness at local and global levels is increasingly apparent. This paper aims to provide an insight into the ongoing COVID-19 crisis, how it can be managed, and what measures are required to deal with a current global international public health concern. Additionally, it shed light on the importance of using wastewater surveillance strategy as an early warning practical tool suitable for massive passive screening, as well as the urgent need for microfluidic technology as a rapid and cost-effective approach tracking SARS-CoV-2 in wastewater.
引用
收藏
页码:1 / 28
页数:27
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