Bronchial carcinoids are uncommon pulmonary neoplasms and represent 1 to 2 % of all lung tumors. In early stage of disease, the mainstay and only curative treatment is surgery. Bronchial carcinoids are generally regarded as low-grade carcinomas and-metastatic dissemination is unusual. The management of the metastatic stage is not currently standardized due to a lack of relevant studies. As bronchial carcinoids and in particular their metastatic forms are rare, we apply treatment strategies that have been evaluated in gastrointestinal and pancreatic neuroendocrine tumors. However, bronchial carcinoids have their own characteristic. A specific therapeutic feature of these metastatic tumors is that they require a dual approach: both anti-secretory for the carcinoid syndrome, and anti-tumoral. (C) 2015 Elsevier Masson SAS. All rights reserved.
机构:
Mem Sloan Kettering Canc Ctr, Thorac Oncol Serv, Div Solid Tumor Oncol, Dept Med, New York, NY 10065 USAMem Sloan Kettering Canc Ctr, Thorac Oncol Serv, Div Solid Tumor Oncol, Dept Med, New York, NY 10065 USA
Litvak, Anya
Pietanza, M. Catherine
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Mem Sloan Kettering Canc Ctr, Thorac Oncol Serv, Div Solid Tumor Oncol, Dept Med,Weill Cornell Med Coll, New York, NY 10065 USAMem Sloan Kettering Canc Ctr, Thorac Oncol Serv, Div Solid Tumor Oncol, Dept Med, New York, NY 10065 USA
机构:
St Louis Univ, Hlth Sci Ctr, Dept Surg, Div Cardiothorac Surg, St Louis, MO 63110 USASt Louis Univ, Hlth Sci Ctr, Dept Surg, Div Cardiothorac Surg, St Louis, MO 63110 USA
Wozniak, TC
Naunheim, KS
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St Louis Univ, Hlth Sci Ctr, Dept Surg, Div Cardiothorac Surg, St Louis, MO 63110 USASt Louis Univ, Hlth Sci Ctr, Dept Surg, Div Cardiothorac Surg, St Louis, MO 63110 USA