4,6-Disubstituted quinazoline derivatives as inhibitors of the MEK5/ERK5 pathway

被引：0
|
作者：
Patel, Saloni [1 ]
Motta, Austin [1 ]
Flaherty, Patrick [1 ]
Bhatt, Akshita [2 ]
Wright, Thomas [2 ]
Cavanaugh, Jane [2 ]
机构：
[1] Duquesne Univ, Med Chem, Pittsburgh, PA 15219 USA
[2] Duquesne Univ, Pharmacol, Pittsburgh, PA 15219 USA
来源：
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY | 2018年 / 256卷
关键词：
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
128
引用
收藏
页数：1
相关论文
共 50 条
  • [1] Identification of pharmacological inhibitors of the MEK5/ERK5 pathway
    Tatake, Revati J.
    O'Neill, Margaret M.
    Kennedy, Charles A.
    Wayne, Anita L.
    Jakes, Scott
    Wu, Di
    Kugler, Stanley Z., Jr.
    Kashem, Mohammed A.
    Kaplita, Paul
    Snow, Roger J.
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2008, 377 (01) : 120 - 125
  • [2] The MEK5/ERK5 Pathway in Health and Disease
    Paudel, Rupesh
    Fusi, Lorenza
    Schmidt, Marc
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 22 (14)
  • [3] MEK5/ERK5 pathway: The first fifteen years
    Drew, Barbara A.
    Burow, Matthew E.
    Beckman, Barbara S.
    BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 2012, 1825 (01): : 37 - 48
  • [4] Optimization of quinazoline derivatives as selective MEK5 inhibitors
    Patel, Saloni
    Motta, Austin
    Flaherty, Patrick
    Bhatt, Akshita
    Wright, Thomas
    Cavanaugh, Jane
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2017, 254
  • [5] Pathophysiological Impact of the MEK5/ERK5 Pathway in Oxidative Stress
    Tusa, Ignazia
    Menconi, Alessio
    Tubita, Alessandro
    Rovida, Elisabetta
    CELLS, 2023, 12 (08)
  • [6] Targeted Avenues for Cancer Treatment: The MEK5?ERK5 Signaling Pathway
    Pereira, Diane M.
    Rodrigues, Cecilia M. P.
    TRENDS IN MOLECULAR MEDICINE, 2020, 26 (04) : 394 - 407
  • [7] Differential role of MEK5α and MEK5β in BMK1/ERK5 activation
    Cameron, SJ
    Abe, J
    Malik, S
    Che, WY
    Yang, J
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2004, 279 (02) : 1506 - 1512
  • [8] Exploration of internal H-bond mimics as MEK5/ERK5 inhibitors
    Gupta, Mohit
    Flaherty, Patrick
    Wright, Thomas
    Cavanaugh, Jane
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2015, 250
  • [9] Contribution of the ERK5/MEK5 pathway to Ras/Raf signaling and growth control
    English, JM
    Pearson, G
    Hockenberry, T
    Shivakumar, L
    White, MA
    Cobb, MH
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (44) : 31588 - 31592
  • [10] Contribution of the ERK5/MEK5 pathway to Ras/Raf signaling and growth control
    English, Jessie M.
    Pearson, Gray
    Hockenberry, Tish
    Shivakumar, Latha
    White, Michael A.
    Cobb, Melanie H.
    Journal of Biological Chemistry, 274 (44): : 31588 - 31592
12345