Effect of off-label use of oncology drugs on pharmaceutical costs: The rituximab experience

GOAL To provide comprehensive and current information concerning the. off-label use of oncology drugs and its effects on pharmaceutical costs. AUDIENCE This activity is designed for pharmacy & therapeutics committee members; group practice directors; physicians specializing in oncology; hospital administrators; and institutional, home-health and/or infusion pharmacists. LEARNING OBJECTIVES Upon completion of this educational activity, the participant should be able to: Interpret the definition and meaning of "off-label" use of a drug. List the pertinent factors that promote, inhibit, or have a mixed influence on off-label use of a drug. Discuss the influence on oncology drug expenditures of off-label use of oncology drugs, with specific emphasis on rituximab costs.